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Volume 13

Research Article

Pathway Crosstalk Analysis of mTOR Gene in Insulin Resistance Mediated Obesity Using Microarray Data

1. Abstract Obesity is defined as the early deposition of adipose tissue caused by a consistent caloric intake that exceeds the individual’s caloric needs. As a worldwide issue, the rising incidence of obesity is a major source of concern—not because of sickness, but because of excess. Obesity is linked to …

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Clinical Report

Thrombocytopenia, With or Without Other Manifestations Related to Gaucher Disease: A Key Diagnostic Clue in Gaucher Disease

1. Abstract 1.1. Aim: Gaucher disease (GD) is a rare autosomal recessive genetic disorder caused by a deficiency in the activity of β-glucocerebrosidase, a lysosomal enzyme. Rapid and accurate diagnosis of GD can maximize the effectiveness of treatment effect. However, diagnosing GD is challenging and tends to be delayed because …

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Research Article

Effect of Ethanolic Extract of Abrus precatorius Leaves on Liver Enzymes in Alloxan-Induced Diabetic Male Rats

1. Abstract Increased metabolic disorders are generally linked to the progression of diabetes mellitus (DM). In this study, we looked into the effects of the ethanolic extract of Abrus precatorius (A. precatorius) leaves on liver enzymes and glycaemia in alloxan-induced diabetic male rats.

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Research Article

Red Blood Cell Transfusions May Have the Stongest Analgesic Effect during Acute Painful Crises in Sickle Cell Diseases

1. Abstract 1.1. Background: The hardened red blood cells (RBC)-induced capillary endothelial damage, inflammation, edema, and fibrosis are initiated at birth, and terminate with disseminated tissue hypoxia, acute painful crises, multiorgan failures, and sudden death even at childhood in the sickle cell diseases (SCD).

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Research Article

Glaucoma-Silent Thief of Sight, a Study on Prevalence and Risk Factors among Adult Patients Attending Ophthalmology Department in a Tertiary Care Hospital

1. Abstract 1.1. Background: Globally, glaucoma is the second leading cause of blindness, next to cataract. As per American academy of ophthalmology study 2014, it was estimated that 76 million people worldwide would suffer from glaucoma by 2020, and it is expected that by 2040 that number will increase to …

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Research Article

Occupational Lead Poisoning in Patients Attended at a University Hospital in Minas Gerais

1. Summary Lead is a heavy metal that has been used since ancient times, including in the production of wine with the aim of sweetening and reducing acidity. In the 1920s, this compound was added to gasoline, believing that it would result in better functioning of the automobile engine.

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Case Report

Amphetamine Induced Reverse Takotsubo Cardiomyopathy: Case Report and Review of Literature

1. Abstract Takotsubo cardiomyopathy is a clinical syndrome characterized by an acute and transient left ventricular dysfunction usually triggered by an emotional or physical stressful event. The hallmark of Takotsubo cardiomyopathy is a presentation similar to acute coronary syndrome but with no evidence of obstructive coronary artery disease.

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Case Report

Papulo Squamous Eruptions of Human Penis Four Cases Reported

1. Abstract 1.1. Background: Noninfectious lesions may be classified as inflammatory and papulo squamous (e.g., psoriasis, lichen planus, lichen nitidus and lichen sclerosis et atrophicus).

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Case Report

Idiopathic Ileocolonic Intussusception in the Elderly: Case Report and Literature Review

1. Abstract 1.1. Background: Adult intussusception is rare, in sharp contrast to childhood intussusception. It’s often considered a distinct disease entity from the paediatric intussusception because of dissimilarities in the aetiology, clinical presentation and management options. Operative treatment is mandatory for the management of colonic intussusception in the adult patient …

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Review Article

Unveiling The Hidden Hazards: Waterpipe Smoking and Its Impact on Health

Review Use of the waterpipe is increasing daily by all ages and sexes. Since waterpipe smoking came to the west, especially among young adults, it has become a global trend [1].

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