1. Abstract
Critical limb ischemia as first diagnosis can lead to amputation in a 20 25% of patients. In this case we present a 49-year-old male with a history of peripheral atherosclerotic arterial disease due to diabetes mellitus type 2 who underwent below the knee amputation and presented with cerebral.

1. Abstract
A concerning clinical symptom that frequently prompts a diagnosis of disorders of sex development (DSD) in children is clitoromegaly. Rare etiologies such androgen-secreting adrenocortical tumours (ACT).

1. Abstract
1.1. Introduction
Solitary Plasmacytomas (SP) are solid tumors originated from local proliferation of mature B lymphocytes that acquire a monoclonal and disordered multiplication pattern, representing five percent of all plasma cell tumors.

1. Introduction
Hirschsprung’s disease (HD) is the most common cause of functional intestinal obstruction in paediatric patients. It is
characterized by contiguous intestinal ganglionitis of the myenteric plexuses of Auerbach and the submucosal

1. Abstract
Killian-Jamieson diverticulum (KJD) is a rare pharyngoesophageal diverticulum arising from the Killian-Jamieson triangle, located below the cricopharyngeal muscle. Its coexistence with thyroid nodules is uncommon and may present diagnostic challenges.

1. Abstract
1.1 Background
The effects of vitamin D on the human body have been the subject of numerous studies. Its beneficial effects on the immune system are promising. The aim of this study was to investigate the correlation between serum vitamin D concentration and cell death evaluated by the quantification of Fas apoptotic factor in healthy patients.

1. Abstract
1.1 Background
Mesh reinforcement can be used as an adjunct in giant paraoesophagal hernias repairs. The use of synthetic mesh is associated with significant morbidity whereas biologic mesh is associated with higher rates of recurrence. We aim to assess the safety and effectiveness of biosynthetic absorbable.

1. Abstract
Lung cancer remains a leading cause of cancer-related mortality globally, and surgical resection is a primary treatment for early-stage disease.