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Metastatic Paraganglioma with Fumarate Hydratase Missense Mutation

1. Abstract 1.1. Background: Majority of Pheochromocytoma (PCC) and paraganglioma (PGL) cases are benign without malignant potential but genetic assessment is recommended for all PCC/PGL patients, because of the associated with ig hereditary germline mutations which play a vital role in pathogenesis of tumorigenesis and metastasis.

Gallstone Ileus

1. Summary Gallstones are hardened deposits of digestive fluid that can form in your gallbladder. Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder holds a digestive fluid called bile that’s released into your small intestine.

Treatment of Bladder Cancer: Anti-PD-1 Drug Treatment Associated Hypothyroidism

1. Abstract Bladder cancer is a common malignant disease of the urogenital tract, and over the past few decades, immunotherapy, based on the principle of activating the patient’s immune system to root out malignant cells, has largely changed the treatment of cancer. Anti-PD-1 drugs include monoclonal antibodies against PD-1 and the PD-1 ligand (PD-L1).

Axonal Polyneuropathy with Anti-Caspr1 Igg1 Paranodal Antibodies

1. Abstract 1.1. Objectives: The main electrophysiological manifestation of autoimmune paranodopathy with anti-contactin-associated protein 1 (Caspr1) positive reported previously was demyelination, with or without axonal involvement. Here, we reported a patient with anti-Caspr1 IgG1 positive who had severe axonal involvement accompanied less evidence of demyelination.

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