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This study investigates the prevalence of psychological comorbid ity in patients with moderate to severe psoriasis vulgaris. Further more, the relation between the type of disorder and the degree of psoriasis severity has been analysed. In 10 German study sites 137 female (61 = 44.5%) and male (76=55.5%) patients that had been diagnosed with moderate or severe psoriasis by a qualified derma tologist were surveyed. The most frequent observed comorbidities were moderate to severe depressive syndromes (23.4%), followed by alcohol syndromes (5.8%) and panic disorders (4.6%). Analysis of relations between the type and severity of disorder and the de gree of psoriasis severity showed no significant correlations. The present data confirm the psychosocial stress of patient with psori asis regardless of the degree of severity.

Biostatistics also known as biometry which means ‘measurement of life’ is a branch of applied statistics which deals with collection, compilation, analysis and interpretation of data related to biomed ical sciences. It provides a key to better understanding of the med ical discipline. Biological data are always subjected to variation and are affected by various environmental, social and genetic fac tors etc. Biostatistics proves a tool for analysing the data taking into account the variability and to elicit meaningful conclusion in research. In this era of evidence-based medicine.

Let me starts with short explanation which led me to write these words to encourage all of you who had experienced or are still experiencing the problem and situation I had gone through. One evening just talking with my partner (who is also a doctor and we operated together in many cases although she is a gynecologist, but our interest is the same in oncology problematic and we started the cooperation in multidisciplinary field of oncology patients) about work we’ve done together, cases and patients to whom we changed the course of life, because most of the cases where defying prec edents in diagnostics and treatment of their diseases and also had impact on the quality and their survival rate.

Oral location of tuberculosis is rare. It admits a clinical polymor phism and poses above all a problem of diagnosis. We report a case of labial tuberculosis in a 16-year-old patient with underlying lymph node localization.

1.1. Introduction: Group of diseases that is originated from the different parts of ovaries and cause production of abnormal cells that divide uncontrolled themselves in the ovaries is known as ovarian cancer. OC is mainly classified into majorly three types on the base of three components of ovaries known as epithelium, stro ma and germinal cells. Approximately, 7000 women develop OC and 4200 of them die every year in UK. In Pakistan the incidence of OC is increasing at the rate of around 13.6%. Approximately 70% cases are diagnosed at later stages.

The aim of this study was to investigate the therapeutic effects of vacuum sealing drainage technology combined with home made anal canal treating the deep burn wounds of the buttocks and perineum. From March 2014 to September 2019, after debride ment of buttocks and perineal granulation wounds in 10 cases with large-area deep burns, autologous postage stamp skin was grafted, homemade silicone tube was inserted and fixed in the anus, contin uous catheterization was performed, and the wounds were treated with vacuum sealing drainage technique for 5-7 days. In 9 cases, most of the skin survived, and the wound was healed after chang ing the dressing. Treating deep burn wounds on the buttocks and perineum with VSD technique and anal insertion of homemade canal significantly improved the skin grafting survival effect, re duced the number of operations and complication, and shortened the treatment time.

1.1. Introduction: Few reports describe squamous cell carcinoma arising in hidradenitis suppurativa. Although rare, the combination of SCC and HS is often associated with early metastasis and high mortality rates.

Parastomal hernia is one of the most common complications after colostomy. Preventive strategies are considerable. For less defect and better mechanical work in abdominal wall, extraperitoneal colostomy is preferred for preventing parastomal hernia. In this work, we demonstrated a new surgery technique through anatomy structures and mechanical principles

The diagnosis of long QT syndrome may be delayed due to ab sence of electrocardiogram (ECG) examination and/or QT interval misdiagnosis. We present the case of a patient who took 8 years before being diagnosed with long QT syndrome. Despite the pres ence of marked QT prolongation and bimodal T waves, automated ECG recording misdiagnosed the patient to be normal. The patient had recurrent syncope; however, repeat ECG examination was not performed because her initial ECG was considered normal.

The interpretation of the acid-base status is key in medical practice, being its most frequent use in critically ill pregnant patients with any type of hemodynamic alteration such as hemorrhagic shock or septic shock, which happens in most cases, states of hypoperfusion systemic that produce alteration in the acid base state that gener ates primary disorders such as acidemia or alkalemia and its met abolic or respiratory components. We make an approach through an arterial or venous blood gas analysis, which has the advantage of an evaluation in a short time to be a diagnosis and thus take medical conduct for a better management of the pregnant patient.