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October 27, 2025


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Long-Term Treatment With BRAF/MEK Inhibitors for Pleomorphic Xanthoastro-  cytoma Grade 3: A Case Report

Long-Term Treatment With BRAF/MEK Inhibitors for Pleomorphic Xanthoastro- cytoma Grade 3: A Case Report

1. Abstract
1.1. Background
Pleomorphic xanthoastrocytoma grade 3 is rare disease classified as a distinct entity in WHO classification 2016. It is usually refractory to a standard therapy for high grade gliomas and has a dismal prognosis.

Pharmacological Awakening: An indispensable tool for Awake Craniotomy: A Case Report

Pharmacological Awakening: An indispensable tool for Awake Craniotomy: A Case Report

1. Abstract
Awake craniotomy allows safe and effective resection of brain tumours near eloquent areas. However, achieving timely and reliable intraoperative awakening is crucial, particularly when pre-existing pathologies and sedative agents delay emergence.

Bipolar TURIS Resection of Large Prostates: The Experience of our Team

Bipolar TURIS Resection of Large Prostates: The Experience of our Team

1. Abstract
Bi polar TURIS resection of the prostate is a well-established method, used over the past two decades for the surgical therapy of benign prostate hyperplasia. According to the EAU guidelines it is best to be applied.

Lateral (Counterclockwise) 1440° Testicular Torsion: A Rare Surgical Observation

Lateral (Counterclockwise) 1440° Testicular Torsion: A Rare Surgical Observation

A 22-year-old male presented with acute right scrotal pain for two hours. Scrotal Doppler ultrasound showed absent intratesticular flow with a “whirlpool” sign. Emergency exploration revealed a markedly edematous and congested testis with a 1440°.

Extrapontine Osmotic Demyelination with Pituitary Necrosis Following Severe  Hyponatremia: A Rare Neuroendocrine Intersection

Extrapontine Osmotic Demyelination with Pituitary Necrosis Following Severe Hyponatremia: A Rare Neuroendocrine Intersection

1. Abstract
1.1. Background
Osmotic demyelination syndrome (ODS) is a rare but significant complication associated with the rapid correction of hyponatremia. Pituitary necrosis, commonly observed in cases of apoplexy, may manifest in susceptible metabolic conditions but is infrequently documented in association with ODS.

A Case of Fanconi Syndrome with Multiple Fractures and Height Loss as Main  Symptoms Caused by Adefovir Dipivoxil

A Case of Fanconi Syndrome with Multiple Fractures and Height Loss as Main Symptoms Caused by Adefovir Dipivoxil

1. Abstract
We present a case of a 57-year-old male who experienced ex- tensive bone pain, difficulty in getting up, weakness in walking, and height loss. He had been taking adefovir dipivoxil tablets for the treatment of hepatitis B.

Decompensation Factors in Heart Failure: Analy

Decompensation Factors in Heart Failure: Analy

1. Abstract
Heart failure (HF) is a major public health issue, particularly in Morocco, where data on precipitating factors remain limited. This study aimed to identify the main triggers of acute decom pensation and to analyze the epidemiological, clinical, and ther apeutic characteristics of patients admitted for acute HF at the.

VA-ECMO in Managing Respiratory Failure and Severe Infection in an Low-Weight  Infant Following Liver Transplantation: Case Report and Literature Review

VA-ECMO in Managing Respiratory Failure and Severe Infection in an Low-Weight Infant Following Liver Transplantation: Case Report and Literature Review

1. Abstract
1.1. Background
Pediatric liver transplantation (pLT) is the standard treatment forend-stage liver disease in children. Perioperative cardiopulmonary complications, including severe infection and respiratory failure, sometimes require extracorporeal membrane oxygenation (ECMO).

PhasixTM non-ST Mesh for Giant Paraoesophageal Hernias – The Way of the Future?

PhasixTM non-ST Mesh for Giant Paraoesophageal Hernias – The Way of the Future?

1.1 Background
Mesh reinforcement can be used as an adjunct in giant paraoesophagal hernias repairs. The use of synthetic mesh is associated with significant morbidity whereas.

Pine Pollen Impacts Hypogonadal Symptoms in Younger Men with Variations in Androgen Levels: Pilot Observations

Pine Pollen Impacts Hypogonadal Symptoms in Younger Men with Variations in Androgen Levels: Pilot Observations

1.1. Purpose
This pilot is a partner trial to a previously published study of older men [1]. The primary goal was to assess the effects of consuming a proprietary tincture form of Pine Pollen.

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