Mandibulofacial dysostosis with microcephaly, Guion-Almeida type (MFDGA) is a rare multiple congenital anomalies syndrome characterized by malar and mandibular hypoplasia, microcephaly, ear malformations with associated conductive hearing loss, esophageal atresia, cleft palate and distinctive facial dysmorphism. Almost all affected individuals have developmental delay and intellectual disability.
Patients with disease progression on first-generation tyrosine kinase inhibitors (TKIs) usually have a poor prognosis. The mechanisms of acquired resistance to epidermal growth factor receptor (EGFR)-TKIs have been widely reported; however, reports of acquired
Progressive prostate cancer is primarily treated with androgen-deprivation therapy. The antiandrogen withdrawal (AAW) response (AAWR) is defined as subjective and/or objective improvement following antiandrogen cessation in patients with elevated prostate-specific antigen (PSA) levels treated with combined androgen blockade (CAB).
A 61-year-old Japanese woman was admitted to our hospital for further examination of generalized bone pain. At age 46 years, the patient was diagnosed with Fanconi syndrome associated with benign monoclonal gammopathy of undetermined significance. At age 56 years, alkaline phosphatase (ALP) increased to 448 IU/mL. A bone biopsy was performed, and osteomalacia was diagnosed.
We presented a case of preterm infant with bilateral colonic inguinal hernia, which was diagnosed radiologically by the initial plain radiograph and subsequent lower gastrointestinal (LGI) study by contrast enema.
Prophylaxis is not only about wearing masks and vaccines, because no vaccine can guarantee 100% immunity to infection. The best vaccines, based on statistical data from previous years, guarantee approximately 55% certainty of not being infected with a bacterial, viral or fungal infection.
Ectopic pregnancy is a rare female emergency that can have a serious impact on the patient and even threaten life. Retroperitoneal ectopic pregnancy as more rare ectopic pregnancy, its diagnosis and treatment are much more difficult.
Air microbubbles are common in the haemodialysis venous return line, especially in the very first minutes of HD session and with high blood flows. They might be damaging for the lungs microcirculation and stimulate the inflammation system
From December 2019, starting from Whuan, COVID-19 pandemic was threatening the entire world population with a major lethal potential. This new infection, with SARS-CoV-2, induces and maintains in human body a significant disturbance in the homeostasis of immune reactions followed by a multiorganic morphological and pathophysiological alterations.
Body packing represents the concealment of illegal substances in a person’s body with the aim of smuggling. Body packers either swallow drug-filled packets or introduce drug-filled packets into their bodies through rectum or vagina.
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