Call

+1 7755157689

Clinical Image

Multiple-scale Computational Studies of Redox-controlled Supramolecular Co-assembly Nanoplatform: Toward Immunochemotherapy-driven Antitumor Augment

Programmed cell death protein 1 (PD1)/programmed death ligand 1 (PD-L1) blockades provide an effective and safe therapeutic option in the field of refractory cancer therapy. However, not more than 30% response rate of most cancers seriously impedes their therapeutic efficacy. Previous investigations have proved the effectiveness of combining chemotherapy with immunotherapy for unsatisfactory response to anti-PD1

View PDF
Short Communication

Case of Anthrax abdominal form in Kazakhstan

Anthrax is a dangerous zoonotic infection that is transmitted from farm animals to humans, when cutting, butchering infected animals, contact with meat and other animal products. Infection occurs by contact, alimentary, aerogenic pathways, while developing corresponding clinical forms – skin /ulcerative, abdominal / intestinal, pulmonary /pneumonic

View PDF
Case Report

Impact of Anesthetics on the ST segment among Patients with Brugada syndrome: Case Series.

1.1. Aim: Brugada syndrome is a canalopathy causing rhythmic sudden death. The use of many drugs such as anesthetics but also many analgesics are contraindicated or not recommended in this pathology. The literature shows a low-level evidence while clinical experience may bring additional knowledge.

View PDF
Review Article

Cytokine storm syndrome in COVID-19 patients: Characteristics and Diagnosis

Cytokine storm syndrome (CSS) is a critical condition induced by a cascade of cytokine activation, characterized by overwhelming systemic inflammation, hyperferritinaemia, haemodynamic instability and multiple organ failure. At the end of 2019, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, and rapidly developed into a global pandemic. There is a dramatic increase of inflammatory cytokines in patients with COVID-19, suggesting the existence of cytokine storm in some critical illness patients. Here, we summarize the pathogenesis, clinical manifestation of CSS, and highlight the current understanding about the recognition and diagnosis of CSS in COVID-19.

View PDF
Research Article

Wen Dan Tang: A Potential Jing Fang Decoction For Headache Disorders

1.1 Background: Chinese herbal medicine is considered relatively safe, inexpensive, and easily accessible. Furthermore, it is becoming increasingly popular in the western countries.

View PDF
Research Article

Deprescribing of Benzodiazepines in the Elderly Using a 3Es Model: A Patient Centered Approach

Benzodiazepines use in the elderly are associated with morbidity including increased falls, fractures, and mortality. The common reason for re-prescribing benzodiazepine by physicians is dependency

View PDF
Case Report

Hepatic Artery Aneurysm masquerading as Abdominal Pain in a child: A rare case report.

1.1. Background: Hepatic artery aneurysm is a rare clinical entity amongst children accounting for 20 % of all the splanchnic artery aneurysms, and if neglected could lead to catastrophic events

View PDF
Research Article

Association between body mass index and severity according of classification of thyroid cancer

1.1. Purpose: Obesity is associated with aggressive pathological features and poor clinical outcomes in breast and prostate cancers. However, the associations between excess weight and prognostic factors for thyroid cancer are uncertain.

View PDF
Case Report

Cardiac transplantation in patients with muscular dystrophy: A case report and review of literature

We report a case of slowly progressive Becker’s muscular dystrophy in a 52-year-old man who required cardiac transplantation for intractable congestive heart failure. A referral was made concerning prognosis of his muscular dystrophy in the multidisciplinary approach to transplant.

View PDF
Case Report

Refractory Vasospasm and Arterial Ischemic Stroke in Meningoencephalitis: Novel Intrathecal Nitroprusside Treatment

Acute stroke in bacterial meningitis in children contributes to high morbidity and mortality. The incidence of stroke in pediatric meningitis is varied, with reports between 8-42%, and associated mortality as high as 25%.

View PDF
error: Content is protected !!