Issue 7

Case presenation of a rare clinical manifestation of a relapse of acute lymphoblastic leukemia in a young woman manifested by growing uterus mimicking a myomatous uterus.

Worldwide there are different systems for providing pharmacy ser vices. Most countries have some element of state assistance, either for all patients or selected groups such as children, and some pri vate provisions. Medicines are financed either through cost sharing or full private. The role of the private services is therefore much more significant. Nationally, there is a mismatch between the num bers of pharmacists and where are they worked, and the demand for pharmacy services.

Chronic fatigue syndrome characterized by severe disabling fa tigue, prolonged post-exertional malaise, and unrefreshing sleep markedly reduces the activities of daily living and impairs the quality of life. Central nervous system dysfunction associated with myalgic encephalomyelitis (ME) has been postulated as the main cause of chronic fatigue syndrome. Recently, oral mino cycline therapy has been reported to exert favorable therapeutic effects in some patients with ME, especially in the initial stage of the disease, although many patients discontinued treatment in the first few days because of acute adverse effects such as nausea and/or dizziness.

Pseudotumor or florid cystitis glandularis is the bladder urothelial of the which mainly affects humans [1,2,3]. It is facilitated by chronic and recurrent irritation of the bladder. Because of its non-specific symptoms, it poses a diagnostic prob lem with malignant bladder tumors [4]. We report 1 case of cystitis glandularis. In the light of this case, we will discuss the diagnostic and therapeutic aspects as well as the prognosis of this condition.

The sudden outbreaking of COVID-19 worldwide has brought into sharp increased burden of economic and treatment. How to simply, quickly and accurately assess the severity of pa tients with COVID-19 in the early stage after hospital admission is essential for healthcare systems.

1.1. Background and Objective: Anastrazole is an aromatase in hibitor used widely in therapy of breast cancer and has been metab olized by CYP3A4 and UGT1A4 in liver. B