Volume 10

Successful Rechallenge of Hepaftocellular Carcinoma with Atezolizumab and Bevacizumab Following Disease Progression

Systemic therapies to treat Hepatocellular Carcinoma (HCC), a cancer with traditionally poor prognosis, have greatly advanced in the last five years with the advent of immunotherapies. The immune checkpoint inhibitor atezolizumab and anti-angiogen ic agent bevacizumab combination therapy is now recommend ed as first line treatment for unresectable HCC. Bevacizumab is associated with an increased […]

Successful Rechallenge of Hepaftocellular Carcinoma with Atezolizumab and Bevacizumab Following Disease Progression Read More »

Positive TESE after Orchidopexy of Bilateral Abdominal Cryptorchidism in an Adult: A Case Report

1.1. Background: Undescended testis is a congenital anomaly that is usually discovered in childhood and undergoes orchidopexy. Undiscovered adult patient with this condition usually undergoes orchiectomy due to atrophy of the testis and a high risk of ma lignancy. Retrieving vital germ cells from adult bilateral non-in tra-abdominal cryptorchidism is a very rare finding and

Positive TESE after Orchidopexy of Bilateral Abdominal Cryptorchidism in an Adult: A Case Report Read More »

A Novel Role of AIM2 Inflammasome-Mediated Pyroptosis in Radiofrequency Ablation of Hepatocellular Carcinoma

1.1. Background: Hepatic inflammation and inflammasome-me diated mechanisms are involved in the pathogenesis of Hepato cellular Carcinoma (HCC), and Absent in Melanoma 2 (AIM2) triggers activation of the inflammasome cascade. Until now, it re mains unclear whether and how AIM2 plays a role in HCC and Radiofrequency Ablation (RFA). This study aimed to investigate whether

A Novel Role of AIM2 Inflammasome-Mediated Pyroptosis in Radiofrequency Ablation of Hepatocellular Carcinoma Read More »

Vascular Abnormality in Hemodialysis-Associated Ischemic Priapism: A Case Report

1.1. Background: Ischemic priapism is a rare condition with ful ly penile rigidity and severe pain. Blood trapping in the penis is a crucial pathophysiology for ischemic priapism, but the reason causing the blood trapping varies. This report presents a case of a 48-year-old male experiencing a vascular abnormality-relevant is chemic priapism during hemodialysis treated

Vascular Abnormality in Hemodialysis-Associated Ischemic Priapism: A Case Report Read More »

Extraskeletal Mesenchymal Chondrosarcoma of Maxillary Sinus :A Case Report

Extraskeletal Mesenchymal Chondrosarcoma (ESMC) originating in the sinonasal tract has rarely been reported. Reports related to its imaging features are even rarer, which makes preoperative diagnosis difficult. Here, we analyse and report the clinical, com puted tomography, and magnetic resonance imaging features of a 25-year-old male patient with pathologically confirmed ESMC in the maxillary sinus,

Extraskeletal Mesenchymal Chondrosarcoma of Maxillary Sinus :A Case Report Read More »

Use of the EIS (Electrical Impedance Segmentography System) in Less-Invasive Surfactant Administration (LISA) in New-Borns Suffering from Respiratory Failure

1.1. Background and Aims: Electrical Impedance Segmentog raphy System simultaneously detects transthoracic impedance changes, which are directly proportional to the amount of gas vol ume in the lung, allowing regional and dynamic monitoring of pul monary ventilation in real time. It is a complementary technique to the most common methods used in the context of

Use of the EIS (Electrical Impedance Segmentography System) in Less-Invasive Surfactant Administration (LISA) in New-Borns Suffering from Respiratory Failure Read More »

Severe Intracranial Subdural Hematoma Following Epidural Anaesthesia in Pregnancy: A Case Report

Severe headache is one of the quite common complication after a dural puncture procedure be it diagnostic (lumbar puncture) or un intentional (e.g., after epidural anaesthesia). Knowing that Postur al Puncture Headache (PDPH) most often becomes the culprit in most cases, many severe and serious etiologists should be assessed though its frequently rare due to

Severe Intracranial Subdural Hematoma Following Epidural Anaesthesia in Pregnancy: A Case Report Read More »

Oxygen Uptake During Walking in Three Types of Microprocessor-Controlled Prosthetic Knee Joints in a Middle-Aged Male with Bilateral Transfemoral Amputation

Individuals with bilateral transfemoral amputations experience great difficulty in prosthetic ambulation in their community be cause of high energy consumption during walking. We present the case of a 47-year-old male with bilateral transfemoral amputation who gradually became more fatigued when walking with pros theses 11 years after completing his first prosthetic training.

Oxygen Uptake During Walking in Three Types of Microprocessor-Controlled Prosthetic Knee Joints in a Middle-Aged Male with Bilateral Transfemoral Amputation Read More »

Functional Correction of the Musculoskeletal Framework – The Basis of the Therapy of a Self-Regulating System

The history of mankind dates back thousands of years, and only in recent years has there been a rapid increase in the percentage of cases, including deformities of the feet and spine. If 60 years ago, flat feet were considered in conjunction with the aging of the body, age-related causes of weight loss, today deformities

Functional Correction of the Musculoskeletal Framework – The Basis of the Therapy of a Self-Regulating System Read More »