Issue 20

Medication related osteonecrosis of the jaw (MRONJ) is a debili tating condition characterized by exposure of non-healing necrotic bone lasting eight weeks or longer in the mandible or maxilla after medication use. Most commonly, MRONJ is a concern for patients receiving bisphosphonate therapy, most commonly for patients undergoing cancer treatment. The use of bisphosphonates in […]

1.1. Background: The observational link between microalbumin and type 2 diabetes (T2DM) is well established. However, it is uncertain if the link is causative. 1.2. Methods: The current study performed Mendelian random ization (MR) on publicly accessible genome-wide association study (GWAS) summary data in order to investigate the causal linkages between microalbumin and T2DM. A

Currently, the primary approach for treating patent ductus arterio sus (PDA) is an alternative non-surgical strategy. Various devices are used for transcatheter closure of PDA. However, the emboli zation of these percutaneous devices is a rare yet severe complica tion. In this case, a 12-year-old girl underwent a successful attempt to close her PDA using

1.1. Background: Type 2 diabetes mellitus and hypertension are two important public health challenges, and both are linked to increased risk of cardiovascular events. Hyperuricemia has re cently emerged as an independent risk factor in the development of type 2 diabetes mellitus and hypertension through several pro posed mechanisms. These include endothelial dysfunction leading to

1.1. Objectives: Hearing loss, the second most frequent sensori neural impairment, could be associated with missense mutations in several genes involved in the development of hearing parts. The re ceptor tyrosine kinase fibroblast growth factor receptor 1 (FGFR1) is known to be expressed in the inner ear and plays an important role in the formation