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Recurrent Pegfilgrastim-Associated Migratory Large Vessel Vasculitis in a Patient with Breast Cancer with Rare HLA Haplotype: A Case Report

1.1. Background: Granulocyte-Colony Stimulating Factor (G-CSF) rarely induces severe systemic vasculitis. However, diagnosing vasculitis can be challenging because clinical mani festations in the early phase are non-specific. We report a case of pegfilgrastim-associated vasculitis in a patient with rare Human Leukocyte Antigen (HLA) genotype and multifactorial disorder during breast cancer chemotherapy.

A Pre-Neoplastic Lesion: A Case Study

The aim of this paper is to report a case of Actinic Dermatosis in an 8-year-old female adult dog with erythematous skin. In the clinical evaluation, the animal presented normal parameters for the species, but, due to the lesions observed, cytological and parasito logical skin tests were requested, which showed the presence of bacteria (cocci), degenerated neutrophils, and dermatophyte fungi, and demodicidosis. Treatment consisted of the use of numerous drugs such as itraconazole, amoxicillin with potassium clavulo nate, predinisolone, Sarolaner, and immunomodulators. In addi tion, the animal has a topical treatment with ketoconazole sham poo and cream. Generally, deep pyoderma that reach the follicle of dogs and form ulcerated wounds, cause a chronic inflammation of the skin, due to the sun’s ultraviolet rays, or familial predisposition or microbial hypersensitivity, or due to other diseases and, usual ly, they are recurrent and do not allow healing. However, in this specific case, the treatment allowed the animal to improve nearly 80%.

Paradoxes of the Theory of Gravity

Showing the contradictions in the physics calculations using the equations of the classical theory of gravitation. Alternatively, in vestigate the physical properties of space objects on the basis of the theory of vortex gravitation, cosmology and cosmogony. The obtained results allow us to evaluate and compare the above objec tive, physical theories.

Modified Elmslie-Trillat Technique for Knee Cap Dislocation: A Retrospective Study with 5 Patients and 1 Year Follow-Up

Knee cap dislocation is a common orthopedic injury that can lead to significant pain, instability and knee dysfunction. Surgical man agement of knee cap dislocation involves various techniques in cluding anteromedialisation and arthroscopic lateral release. The modified Elmslie-Trillat technique combines these two procedures for a more comprehensive and effective treatment. The aim of this retrospective study was to evaluate the clinical outcomes of the modified Elmslie-Trillat technique for knee cap dislocation in a series of 5 patients.

The Chinese the Asia Tallest: How and When?

Japan was a forerunner in rapid economic development in NE Asia after WWII, followed by South Korea with two decades behind due to Korean War (1950-53). Children in Japan started to increase in height radically in 1960, as the inputs to health, food consumption increased in quantity and quality and then quit increasing in height in the mid-1990s. They were overtaken by Korean peers by 3.0 cm in the mid-2000s, that plateaued in height afterwards. The Great Chinese Famine, caused by the Great Leap Forward led to severe malnutrition in China nationwide in 1975-1985. China’s economy has made fast development since then. Very little is known about the trend in stature, “net measure that captures the supply of inputs to health” (Steckel) in China since then. Based on nationwide sur veys, CNSSCH, this note explores trends in children’s height in China over the period of 1985 to 2020.

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