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February 22, 2025


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Recurrent Swelling of the Lower Limbs (Lymphedema) As a Manifestation of the Idiopathic Hypereosinophilic Syndrome

Hypereosinophilic syndrome is an unexplained disorder characterized by prominent blood and bone marrow eosinophilia and tissue eosinophil infiltration. It can cause damage/dysfunction of multiple organs, mainly involving the skin, heart, lungs, gastrointestinal tract and the nervous system.

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Successful Treatment of Systemic Sarcoidosis with Tranilast

Although the effectiveness of tranilast in cutaneous sarcoidosis has been reported, its recorded adoption in systemic sarcoidosis is finite. We report a case of huge subcutaneous sarcoidosis with multiple organ involvement and systemic symptoms relieved quickly after the treatment of tranilast, suggesting that tranilast is expected to become the first-line therapy of sarcoidosis as for its less side effect.

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DPP – 4 Inhibitors in Type 2 Diabetes Mellitus – A Panoramic Review

1. Introduction Diabetes mellitus, commonly referred to as diabetes, is a chronic metabolic disorder characterized by elevated blood glucose levels, known as Hyperglycaemia. Its results from the body’s inability to effectively utilize or produce insulin, a hormone essential for regulating blood sugar. Diabetes is a complex condition with multiple forms, including type 1 diabetes, type 2 diabetes, and gestational diabetes, each with distinct etiologies and pathophysiological mechanisms.

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