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Prenatal Diagnosis of Denys-Drash Syndrome

Denys-Drash syndrome consists of the triad of progressive nephropathy characterised by diffuse mesangial sclerosis (DMS), genital abnormalities, and Wilms tumour. Nephropathy may range from early onset proteinuria to nephrotic syndrome to end stage renal failure. Genital malformations affects both external and internal genitalia.

Impactions in Orthodontics – A Review

Tooth eruption involves the migration of the teeth from a nonfunctional position within the bone to a functional position in the jaw. In orthodontic practice, it is inevitable that one will encounter eruptive abnormalities such as impacted, ectopically erupting, transposed, congenitally missing, and supernumerary teeth.

Successful Treatment of Systemic Sarcoidosis with Tranilast

Although the effectiveness of tranilast in cutaneous sarcoidosis has been reported, its recorded adoption in systemic sarcoidosis is finite. We report a case of huge subcutaneous sarcoidosis with multiple organ involvement and systemic symptoms relieved quickly after the treatment of tranilast, suggesting that tranilast is expected to become the first-line therapy of sarcoidosis as for its less side effect.

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