February 2, 2023

1.1. Background: Hepatic inflammation and inflammasome-me diated mechanisms are involved in the pathogenesis of Hepato cellular Carcinoma (HCC), and Absent in Melanoma 2 (AIM2) triggers activation of the inflammasome cascade. Until now, it re mains unclear whether and how AIM2 plays a role in HCC and Radiofrequency Ablation (RFA). This study aimed to investigate whether RFA induces pyroptosis in HCC through AIM2-inflam masome signaling in vivo and in vitro.

1.1. Background: Ischemic priapism is a rare condition with ful ly penile rigidity and severe pain. Blood trapping in the penis is a crucial pathophysiology for ischemic priapism, but the reason causing the blood trapping varies. This report presents a case of a 48-year-old male experiencing a vascular abnormality-relevant is chemic priapism during hemodialysis treated with a canerno-glan dular shunt

Extraskeletal Mesenchymal Chondrosarcoma (ESMC) originating in the sinonasal tract has rarely been reported. Reports related to its imaging features are even rarer, which makes preoperative diagnosis difficult. Here, we analyse and report the clinical, com puted tomography, and magnetic resonance imaging features of a 25-year-old male patient with pathologically confirmed ESMC in the maxillary sinus, hoping to improve the understanding and diagnosis of this disease, reduce misdiagnosis and missed diagno sis. Extraskeletal mesenchymal chondrosarcoma in the maxillary sinus demonstrate typical imaging features, such as calcification , inhomogeneous enhancement, hemorrhage, necrosis and cystic degeneration.

1.1. Background and Aims: Electrical Impedance Segmentog raphy System simultaneously detects transthoracic impedance changes, which are directly proportional to the amount of gas vol ume in the lung, allowing regional and dynamic monitoring of pul monary ventilation in real time. It is a complementary technique to the most common methods used in the context of respiratory failure in the new-born. We want to demonstrate how a simple, non-invasive, free of radiation bedside monitoring method can provide us extemporaneous feedback about the ventilatory condi tion of the new-born suffering from respiratory failure and treated with surfactant administration, even before the aid of an X-ray is required.