April 13, 2022

NSCLC patients who had sensitive EGFR mutation had great pos sibility to get benefit from EGFR-TKIs. But this efficacy was re lied on related EGFR mutation, if related EGFR mutation changed, resistance would happened. In our report, we did next generation sequencing(NGS) each time the patient had progression.

This is a brief commentary to our article “Defecation delay in pa tients after lung tumor surgery: a prospective nested case-control study” [1]. The author Chen used to be a resident and rotate in different departments of surgery and find that discomfort related to defecation is quite common in patients receiving various opera tion under general anesthesia. Even operations not associated with gastrointestinal tract like thyroidectomy may develop a need for laxatives though patients recovered quickly after the procedure. However, this problem is usually not fully appreciated and just a few studies focused on it.