February 27, 2022

Clinical decision requires to infer great, diverse and not suitably organized quantity of information and having low time to decide. The therapeutic choice is fundamental to formulate a strategy to avoid complications and to achieve favorable results, being more important in some specialties. In addition, medical decision-mak ers are overloaded with clinical tasks, have an intense work rate and are subject to a great demand, and are prone to greater tiredness.

1.1. Introduction: Medical education worldwide is undergoing a pedagogical renovation movement; medical simulation is one of the revolutionary educational tools whose aim is to improve the medical knowledge, technical and non-technical skills of health professionals, while ensuring patient safety. Many studies have dealt with the contribution of simulation in cardiology, however no studies have been done on the management of cardiovascular emergencies in pregnant women by simulation.

Cardiac myxomas are the most common primary cardiac tumor. Clinical findings are numerous and range from general manifesta tions to symptoms related to intra-cardiac obstruction or systemic embolization. Echocardiography is the key exam for the diagnosis and surgery allows tumor resection and the prevention of compli cations.

Several severe acute respiratory Syndrome Coronavirus 2 (SARS CoV-2) vaccines have been approved for clinical use. However, most studies use the SARS-CoV-2-neutralizing antibody titers in duced after immunization as an evaluation indicator, and the role of cellular immune responses in the protective efficacy of vaccines is rarely mentioned. The synergistic effect of virus-specific humor al immunity and the cellular immune response helps the host fight against viral infection. A follow-up analysis of SARS-CoV-2-in fected individuals indicated that the early appearance of specific T cell responses is strongly correlated with mild symptoms and that individuals with pre-existing SARS-CoV-2 nonstructural pro tein-specific T cells are more likely to be immune to infection. These findings suggest the important role of cellular immunity in the fight against SARS-CoV-2 infection.