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March 11, 2025


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Red Blood Cell Transfusions May Have the Stongest Analgesic Effect during Acute Painful Crises in Sickle Cell Diseases

1. Abstract
1.1. Background: The hardened red blood cells (RBC)-induced capillary endothelial damage, inflammation, edema, and fibrosis are initiated at birth, and terminate with disseminated tissue hypoxia,
acute painful crises, multiorgan failures, and sudden death even at childhood in the sickle cell diseases (SCD).

Effect of Ethanolic Extract of Abrus precatorius Leaves on Liver Enzymes in Alloxan-Induced Diabetic Male Rats

1. Abstract
Increased metabolic disorders are generally linked to the progression of diabetes mellitus (DM). In this study, we looked into the effects of the ethanolic extract of Abrus precatorius (A. precatorius)
leaves on liver enzymes and glycaemia in alloxan-induced diabetic male rats.

First Case in Italy of a Patient with Sifrim-Hits-Weiss Syndrome [Sihiwes] Described from an Audiological and Neuropsychological Point of View

1. Abstract
Sifrim-Hitz-Weiss syndrome [SIHIWES] is a multi-systemic neurodevelopmental disorder caused by heterozygous missense variants in chromodomain helicase DNA-binding protein 4 [CHD4].

Metastatic Paraganglioma with Fumarate Hydratase Missense Mutation

1. Abstract
1.1. Background: Majority of Pheochromocytoma (PCC) and paraganglioma (PGL) cases are benign without malignant potential but genetic assessment is recommended for all PCC/PGL patients, because of the associated with ig hereditary germline mutations which play a vital role in pathogenesis of tumorigenesis and metastasis.

Principles of Resection for Pancreatic Cancer – Pancreaticogastroanastomosis Experiences – Study

1. Summary
Carcinoma of pancreas is also called ductal carcinoma, adenocarcinoma, is the most common type of pancreatic cancer, accounting for more than 90 percent of pancreatic cancer diagnoses. This cancer occurs in the lining of the ducts in the pancreas.

Reproductive Outcomes after Myomectomy: Intracapsular Rotary-cut Procedure (IRCP) Versus Conventional Myomectomy(CM)

1. Abstract
1.1. Objective: There is a substantial body of literature on fertility outcomes following conventional myomectomy (CM), whereas limited research exists regarding fertility outcomes after Intracapsular
Rotary-cut Procedure (IRCP).Our aim was to compare the reproductive outcomes between IRCP and CM.

The DTR Technique – Drilling Through Roots of Posterior Teeth for Anatomically Guided Implant Placement – Case Series with 8 Year Follow Up

1. Introduction
The surgical placement of dental implants for damaged or missing teeth is a well-established technique that has been well-documented in the literature, demonstrating a high percentage of success.
In recent decades, there has been an increasing acceptance of immediate implant placement (IIP) following the first evidence of placing implants into newly extracted sockets provided by Schulte and Heimke and Schulte et al.

The Writing: Method to Work with the Interiority

I have never associated the term “therapeutic” with the meaning of a resolutory and definitive act for the person, but I have always glimed between it aims the indication of a path to the support and protection of those who live a precarious balance, both in Relation to their physical wellbeing both for their delicate inner condition, for their own self-image.

Therapeutic Writing

1. Abstract
The concept about the “therapeutic writing” has its beginning from an autobiographic work, realized in 2003, whose title is Letters to a real interlocutor. My sense.

Treatment of Bladder Cancer: Anti-PD-1 Drug Treatment Associated Hypothyroidism

1. Abstract
Bladder cancer is a common malignant disease of the urogenital tract, and over the past few decades, immunotherapy, based on the principle of activating the patient’s immune system to root out malignant cells, has largely changed the treatment of cancer. Anti-PD-1 drugs include monoclonal antibodies against PD-1 and the PD-1 ligand (PD-L1).

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