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October 1, 2025


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Clinical-Pathological Analysis of 37 Oral Squamous Cell Carcinomas in Tucumán, Northwestern Province of Argentina: Immunohistochemical Study of p53 In Selected Cases

1. Abstract
Oral squamous cell carcinoma (OSCC) represents 3% of all malignant neoplasms. Considering the observed regional occurrence of
OSCC, the aim of this study was to analyze the incidence and clinical characteristics of patients with primary carcinoma.

Identification of Prototheca from the Cerebrospinal Fluid of a Cat with Neurological Signs

1. Simple Summary
The genus Prototheca encompasses unicellular algae that are achlorophyllous and widespread in the environment. The genus is now included in the family Chlorellaceae, belonging to the order Chlorellales, which is included in the class, Trebouxiophyceae. Prototheca have repeatedly been reported to infect vertebrates.

A Case-Report Highlighting Effects of PMF and Camel Milk on a Multiple Sclerosis Patient

1. Abstract
1.1. Background: PMF is proved to be highly selective agent for many types of cancer in tissue culture levels and in the animal model.

Meckel Diverticulum as Severe Complication of Enterorrhagia

1. Summary
Meckel diverticulum is one of the possible reasons of acute hemorrhagic emergency cases which leads to massive enterorrhagia with life threatening situation.

Notes on Diabetes

1. Introduction
Diabetes Mellitus (DM) comprises a heterogeneous group of systemic, chronic diseases of unknown cause, with variable degrees of hereditary predisposition and the participation of various environmental
factors that affect the intermediate metabolism of carbohydrates, proteins and fats that They are pathophysiologically associated with a deficiency in the quantity, timing of secretion and/or action of insulin [1-10].

Sequential Bispecific Antibodies in Functional and Clinical High Risk Multiple Myeloma, Manifesting with Extramedullary Disease at Relapse: A Case Report

1. Case Report
Despite recent advances in the treatment of multiple myeloma (MM), the disease remains incurable. Triple class refractory (TCR) patients, defined as refractory to a proteasome inhibitor (PI), immunomodulatory agent (IMiD), and anti-CD38 monoclonal antibody have demonstrated to have especially poor outcomes with a median overall survival of less than 1 year [1-3].

Silencing HO-1 Inhibits Oxidative Stress, Restores Expression of Members of Iron Metabolism, and Attenuates the in Vitro Carcinogenic Activity of PCBs

1. Abstract
HMOX1 (HO-1) might be involved in the mechanism of polychlorinated biphenyl (PCB)-induced tumorigenic effects through influences on iron-metabolism factors. This work aimed to investigate
the in-vitro effect of HO-1 silence on the PCBs treated BC cells. The breast cancer cell lines MCF-7 and MDA-MB-231 were used for analysis of in-vitro functions.

Antibiotic Prescription and Consumption in Brazil: Impact in the Global Health

1. Abstract
Despite the antibiotic sale prohibition without medical prescription since 2010, excessive and often inappropriate antibiotic prescription and self-medication, are still common practices in Brazil.
Indiscriminate antibiotic use is directly involved with the dissemination of resistant bacteria causing serious infections increasingly difficult to treat.

Prednisone and Tranexamic Acid Oral Treatment in Chronic Subdural Hematoma: Case Series

1. Abstract
1.1. Background: During the Covid era, the avoidance of suggest to come to the hospital for patient with simptoms and pathology which can be treated conservatively, have been a diffused habit. Chronic subdural hematoma is a well known neurosurgical pathology, which can be treated by surgical intervention or conservative treatment, and the choice between this two modality of treatment has to be made on the base of many parameters.

The Invention of the Mid-Infrared Generating Atomizer and its Human and Veterinary Medicinal Applications– A Pioneering Research

1. Abstract
1.1. Background and Objectives: In the current scenario, there are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on a molecular basis.

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