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April 4, 2025


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Volume 9

Persistence HFRS infection risk among migrant outdoor labours in Shanghai, China: a case report

Hemorrhagic fever with renal syndrome (HFRS), a rodent-borne disease caused by hantaviruses, is clinically characterized by fe ver, circulatory collapse with hypotension, hemorrhage, and acute kidney injury. China has the largest number of HFRS cases world wide, with outbreaks occurring in both eastern coastal cities and inland cities, occasionally resulting in death, it is necessary to find loopholes in prevention and control measures to reduce the occur rence of such infectious diseases.

Persistence HFRS infection risk among migrant outdoor labours in Shanghai, China: a case report Read More »

Effects of statin use on length of hospital stay and clinical outcome in hospitalized COVID-19 patients: A retrospective cohort study

The search for effective COVID-19 management strategies con tinues to evolve. Severity of COVID-19 has been reported to be positively correlated with a concomitant rise in inflammatory cytokine levels (1, 2). Statins (3-hydroxy-3-methylglutaryl co enzyme A (HMG-CoA) reductase inhibitors) are widely used for dyslipidemia for primary and secondary prevention of cardiac and cerebrovascular events. Statins also have anti-inflammatory ef fects, including reducing C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interferon gamma (IFNγ) which has been hypothesized in reducing the severity of COVID-19. In this study, we aimed to assess the effects of statin on the length of hospital stay and clinical outcome in patients with COVID-19.

Effects of statin use on length of hospital stay and clinical outcome in hospitalized COVID-19 patients: A retrospective cohort study Read More »

Post angiography skin necrosis treated with gracilis muscle flap- A case report

The use of the muscle flaps for the management of complex groin wound with exposed vessels provide effective and safe coverage. The choice of flap is important depending on the size of the wound which gives adequate healthy tissue coverage delivering oxygen and antibiotic to the infected wound bed, which can prevent cata strophic events like vessel blow out. We report here usage of retro flexed gracilis muscle flap for successful covering of the exposed femoral vessels post angiography procedure.

Post angiography skin necrosis treated with gracilis muscle flap- A case report Read More »

A difficult diagnosis of intraductal papillary neoplasia of the bile duct (IPNB): A case report and review of surveillance, epidemiology, and end results

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare biliary tumor characterized by papillary growth in the bile duct, a high risk of malignant transformation, and an unknown prognosis. IPNB diagnosis has always been challenging, especially when the tumor is difficult to detect by imaging. Smaller IPNB tumors are difficult to diagnose preoperatively using only noninvasive imag ing examination, and bile duct stones can impact the successful diagnosis of IPNB.

A difficult diagnosis of intraductal papillary neoplasia of the bile duct (IPNB): A case report and review of surveillance, epidemiology, and end results Read More »

The clinical characteristics and the pathogenic gene mutations in two sporadic cases with tuberous sclerosis complex

Tuberous sclerosis complex (TSC) is an autosomal-dominant dis order characterized by hamartomas in multiple organ systems. Variants in the TSC1 and TSC2 gene lead to the dysfunction of the hamartin or tuberin proteins, respectively, which causes tuberous sclerosis complex.

The clinical characteristics and the pathogenic gene mutations in two sporadic cases with tuberous sclerosis complex Read More »

Severe bradycardia that lead to Mobitz type two heart block in a pregnant African American female who got infected with covid-19

Impact of COVID-19 on certain patient populations have been described extensively in several studies. However, the impact of COVID-19 on pregnant patients and how they can be safely man aged still remains elusive. We report a case of a 30-year-old Afri can American pregnant woman who presented with a six (6) day history of cough with whitish expectorant, exertional shortness of breath and diffuse generalized body aches. She was admitted and managed with a bolus dose of Remdesivir, however on day eight (8) she had symptoms of dyspnea, chest pain, fatigue and became diaphoretic and pale. Physical exam revealed severe bradycardia and EKG studies showed second degree Mobitz type 2 heart block.

Severe bradycardia that lead to Mobitz type two heart block in a pregnant African American female who got infected with covid-19 Read More »

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