A case of methotrexate-associated lymphoproliferative disorder after resection of an accidentally detected enlarged thyroid tumor
1.1. Introduction: We herein present a case of methotrexate-associated lymphoproliferative disorder (MTX-LPD) with a diagnosis of an 8-mm thyroid tumor of class III cytology that grew three times larger during 2 years 8 months before resection.
Publications trends in major anesthesiology journals: A 20-year analysis of five top-ranked journals in the field
1.1. Background: With the intention to quantify the importance of a medical journal, the impact factor (IF) was introduced. It has become a de facto fictive rating instrument of the importance of medical journals. Also, it is often used to asses the value of the individual publications within the specific journal. The aim of the present study was to analyze publication trends over 20 years in five high-ranked anesthesiology journals.
High LOXL1-AS1 lncRNA expression is a prognostic biomarker for poor prognosis in cholangiocarcinoma
Cholangiocarcinoma (CHOL) is the most common malignant tumor of hepatobiliary system. The present study investigated the clinical significance and biological functions of LOXL1-AS1 in CHOL. The poor survival in CHOL has a probable prognostic molecular marker known as the LOXL1-AS1, and LOXL1-AS1 may be an important regulator of immune cell infiltration
Cardiopulmonary bypass graft in a post COVI-19 thalassemic patient
Thalassemia is of the most frequent haemoglobinopathy that includes a heterogeneous group of inherited autosomal recessive pathologies caused by defective synthesis of globin subunit that comprise haemoglobin production. In β-thalassemia, insufficient quantities of β-globin chains are produced, causing ineffective erythropoiesis and microcytic hypochromic anaemia.
Rapid diagnosis of acute respiratory infections by multiplex endpoint PCR technology
1.1. Introduction: The multiplex endpoint PCR technology offers a number of potential advantages, results are available in a matter of hours rather than days, the extreme sensibility facilitates detection of even minutes the amounts of pathogen DNA in clinical samples and the test is
Cancer cells – their origin
The formation of cells in the body, like their mutation, is a process associated with a violation of the composition and structure of a substance (cells) formed under the influence of an external field surrounding it
Mayer- Rokitansky- KUster- Hauser Syndrome (MRKH SYNDROME)- An unusual case of primary amenorrhoea
The onset of mestruation is a significant milestone of sexual maturation in a girl child. Although there are numerous causes of primary amenorrhoea, Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, also known as Müllerian aplasia is one the extremely rare cause of primary amenorrhoea which is usually picked up by suitable imaging technique like Magnetic Resonance Imaging (MRI). MRKH is a rare congenital disorder that is characterised by aplasia of the uterus and upper part of the vagina with normal secondary sexual characters and a normal female karyotype (46, XX).
Delirium Care Pathway MoDelirium Care Pathway Model Design: STOP DELIRIUMdel Design: STOP DELIRIUM
We present a delirium care pathway model that we have dubbed STOP DELIRIUM. Due to delirium’s magnitude and effect in elderly hospitalized patients, we recommend hospitals must have a delirium care pathway for early identification, prevention, and delirium management
Catha Edulis Forsk and Its Adverse Effects On Health: Current and Ongoing Factuality
The leaves of khat tree have an aromatic odor and an astringent and slightly sweet taste. It has been widely chewed for its stimulant action by the population in these regions for many years. Its young buds and tender leaves contain amphetamine-like psycho active substances, which produce euphoria and stimulation
A case of a pair of siblings with moyamoya disease
A pair of siblings with Moyamoya disease (MMD) were admitted to our department and treated with superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis and encephalo-myo- synangiosis (EMS).