Issue 15

1.1. Background: With the intention to quantify the importance of a medical journal, the impact factor (IF) was introduced. It has become a de facto fictive rating instrument of the importance of medical journals. Also, it is often used to asses the value of the individual publications within the specific journal. The aim of the present study was to analyze publication trends over 20 years in five high-ranked anesthesiology journals.

Cholangiocarcinoma (CHOL) is the most common malignant tumor of hepatobiliary system. The present study investigated the clinical significance and biological functions of LOXL1-AS1 in CHOL. The poor survival in CHOL has a probable prognostic molecular marker known as the LOXL1-AS1, and LOXL1-AS1 may be an important regulator of immune cell infiltration

Thalassemia is of the most frequent haemoglobinopathy that includes a heterogeneous group of inherited autosomal recessive pathologies caused by defective synthesis of globin subunit that comprise haemoglobin production. In β-thalassemia, insufficient quantities of β-globin chains are produced, causing ineffective erythropoiesis and microcytic hypochromic anaemia.

1.1. Introduction: The multiplex endpoint PCR technology offers a number of potential advantages, results are available in a matter of hours rather than days, the extreme sensibility facilitates detection of even minutes the amounts of pathogen DNA in clinical samples and the test is