A Mild form of Familial Mediterranean Fever Associated with aPolymorphisms C.Nt 1588,-69G>
Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutation(s) in the Mediterranean fever (MEFV, pyrinmarenostrin) gene. FMF is characterized by recurrent fever crisis combined with serosal, synovial, or cutìaneous inflammation. Until now more than 304 sequence variants have been recorded. Here, we describe a case of mild FMF confirmed by analysis of the MEFV gene, characterized by polymorphism c1588-69G>A.