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November 2, 2025


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Volume 13

Acute Chest Syndrome and Coronavirus Disease May be Genetically Determined Exaggerated İmmune Response Syndromes in Capillaries all Over the Body

1. Abstract 1.1. Background: Sickle cell diseases (SCD) are severe inflammatory processes mainly on capillaries as the main distributors of hardened red blood cells (RBC) into the tissues. Moderate and severe coronavirus disease (COVID-19) may also be a genetically determined exaggerated inflammatory process on capillary endothelium all over the body terminating with high mortality rates in some families.

Acute Chest Syndrome and Coronavirus Disease May be Genetically Determined Exaggerated İmmune Response Syndromes in Capillaries all Over the Body Read More »

Antenatally Detected Megaurethra: A Challenging Prenatal Diagnosis of Prune Belly Syndrome

1. Abstract Prune Belly Syndrome (PBS) is a rare congenital disorder characterized by a triad of urinary tract dilatation, abdominal wall musculature deficiency and bilateral cryptorchidism. Here, we present a case report of a 31-year-old woman referred to our department for ultrasound examination at 22 weeks and 2 days of gestation due to fetal bladder dilation.

Antenatally Detected Megaurethra: A Challenging Prenatal Diagnosis of Prune Belly Syndrome Read More »

Thrombocytopenia, With or Without Other Manifestations Related to Gaucher Disease: A Key Diagnostic Clue in Gaucher Disease

1. Abstract 1.1. Aim: Gaucher disease (GD) is a rare autosomal recessive genetic disorder caused by a deficiency in the activity of β-glucocerebrosidase, a lysosomal enzyme. Rapid and accurate diagnosis of GD can maximize the effectiveness of treatment effect. However, diagnosing GD is challenging and tends to be delayed because its early clinical manifestations and severity are highly heterogeneous and nonspecific, and may present at any age from early infancy to mature adulthood.

Thrombocytopenia, With or Without Other Manifestations Related to Gaucher Disease: A Key Diagnostic Clue in Gaucher Disease Read More »

Pathway Crosstalk Analysis of mTOR Gene in Insulin Resistance Mediated Obesity Using Microarray Data

1. Abstract Obesity is defined as the early deposition of adipose tissue caused by a consistent caloric intake that exceeds the individual’s caloric needs. As a worldwide issue, the rising incidence of obesity is a major source of concern—not because of sickness, but because of excess. Obesity is linked to a number of ailments, the most serious of which might be type 2 diabetes, and the fundamental reason for this link is obesity’s proclivity to develop insulin resistance.

Pathway Crosstalk Analysis of mTOR Gene in Insulin Resistance Mediated Obesity Using Microarray Data Read More »

Concha Bullosa of the Inferior Turbinate: A Rare Anatomical Cause of Nasal Obstruction

1. Abstract 1.1. Background: Cavity formation filled with air in the inferior turbinate is very rare. Hitherto, only 13 cases of inferior turbinate concha bullosa have been reported. I present an additional case discovered during the evaluation of a patient with chronic rhinosi- nusitis.

Concha Bullosa of the Inferior Turbinate: A Rare Anatomical Cause of Nasal Obstruction Read More »

Idiopathic Ileocolonic Intussusception in the Elderly: Case Report and Literature Review

1. Abstract 1.1. Background: Adult intussusception is rare, in sharp contrast to childhood intussusception. It’s often considered a distinct disease entity from the paediatric intussusception because of dissimilarities in the aetiology, clinical presentation and management options. Operative treatment is mandatory for the management of colonic intussusception in the adult patient as many cases are associated with bowel tumours.

Idiopathic Ileocolonic Intussusception in the Elderly: Case Report and Literature Review Read More »

Amphetamine Induced Reverse Takotsubo Cardiomyopathy: Case Report and Review of Literature

1. Abstract Takotsubo cardiomyopathy is a clinical syndrome characterized by an acute and transient left ventricular dysfunction usually triggered by an emotional or physical stressful event. The hallmark of Takotsubo cardiomyopathy is a presentation similar to acute coronary syndrome but with no evidence of obstructive coronary artery disease.

Amphetamine Induced Reverse Takotsubo Cardiomyopathy: Case Report and Review of Literature Read More »

Occupational Lead Poisoning in Patients Attended at a University Hospital in Minas Gerais

1. Summary Lead is a heavy metal that has been used since ancient times, including in the production of wine with the aim of sweetening and reducing acidity. In the 1920s, this compound was added to gasoline, believing that it would result in better functioning of the automobile engine.

Occupational Lead Poisoning in Patients Attended at a University Hospital in Minas Gerais Read More »

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