Volume 12

1. Abstract 1.1. Background and Objectives: In the current scenario, there are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on a molecular basis.

1. Abstract 1.1. Background: In pediatric Crohn’s disease (CD), anti-TNF-ɑ medications remain a mainstay of therapy, but primary nonresponse and secondary loss of response remain significant concerns. Enteral nutritional therapy is also an effective therapy in pediatric CD. The aim of this study was to assess the impact of concomitant enteral nutrition (EN) with anti-TNF-α therapy compared to anti- TNF-ɑ monotherapy on outcomes in pediatric CD.

1. Abstract Rhino-orbito-cerebral mucormycosis (ROCM) as a rare but life-threatening fungal infection always resulted in unilateral clinical signs, which included ptosis, proptosis, periorbital swelling, facial swelling and dysesthesia.

1. Abstract Abdominal wall endometriosis (AWE) is un uncommon type of endometriosis that develops more often after a surgical procedure. Typically, wide surgical excision is the treatment of choice when hormonal therapy fail to control the symptoms, although negative margins are necessary to minimize recurrences.

1. Abstract 1.1. Objective: To summarize the treatment and nursing experience of a patient with stage 4 pressure ulcers in the sacrococcygeal region and buttocks. Methods: On April 9, 2023, a patient with stage 4 pressure sores on the tail and buttocks was admitted to the Burn, Plastic and Cosmetic Department of Baise People’s Hospital as an example.

1. Abstract 1.1. Background: The absorption process of Xin-su-ning Capsules (XSNC) in rats has not been reported, so this study studied the absorption components of XSNC in rat plasma and myocardial tissue based on the chemical composition characterization methods of XSNC.

1. Abstract 1.1. Background: Migraine is a disorder that has a pulsating, unilateral character, which worsens with physical exertion and hinders the quality of life of people who suffer from it. Even though there are several comorbidities related to the disease, pain control is the main objective and neuromodulation can be used in patients who have some drug intolerance or capacity for non-pharmacological management.

1. Abstract Mesenteric panniculitis is a non-specific inflammatory condition of the mesenteric adipose tissue most often revealed by non-spe- cific clinical signs. Therapeutic options have not yet been stand- ardised. Consequently, Its diagnosis and treatment remain a chal- lenge for professionals.

1. Summary The pathophysiology of macrosomia is related to the associated maternal or fetal condition that accounts for its development. In general, poorly controlled diabetes, maternal obesity, and excessive maternal weight gain are all associated with macrosomia and have intermittent periods of hyperglycemia in common.

1. Abstract 1.1. Introduction: Meckel’s diverticulum (MD) is the most commoncongenital anomaly of the gastrointestinal system. It is caused by an incomplete obliteration of the vitelline duct. Rarely, it can present with complications like torsion and gangrene formation.