Volume 12

1. Abstract Oral squamous cell carcinoma (OSCC) represents 3% of all malignant neoplasms. Considering the observed regional occurrence of OSCC, the aim of this study was to analyze the incidence and clinical characteristics of patients with primary carcinoma.

1. Simple Summary The genus Prototheca encompasses unicellular algae that are achlorophyllous and widespread in the environment. The genus is now included in the family Chlorellaceae, belonging to the order Chlorellales, which is included in the class, Trebouxiophyceae. Prototheca have repeatedly been reported to infect vertebrates.

1. Abstract 1.1. Background: PMF is proved to be highly selective agent for many types of cancer in tissue culture levels and in the animal model.

1. Summary Meckel diverticulum is one of the possible reasons of acute hemorrhagic emergency cases which leads to massive enterorrhagia with life threatening situation.

1. Introduction Diabetes Mellitus (DM) comprises a heterogeneous group of systemic, chronic diseases of unknown cause, with variable degrees of hereditary predisposition and the participation of various environmental factors that affect the intermediate metabolism of carbohydrates, proteins and fats that They are pathophysiologically associated with a deficiency in the quantity, timing of secretion and/or action of insulin [1-10].

1. Case Report Despite recent advances in the treatment of multiple myeloma (MM), the disease remains incurable. Triple class refractory (TCR) patients, defined as refractory to a proteasome inhibitor (PI), immunomodulatory agent (IMiD), and anti-CD38 monoclonal antibody have demonstrated to have especially poor outcomes with a median overall survival of less than 1 year [1-3].

1. Abstract HMOX1 (HO-1) might be involved in the mechanism of polychlorinated biphenyl (PCB)-induced tumorigenic effects through influences on iron-metabolism factors. This work aimed to investigate the in-vitro effect of HO-1 silence on the PCBs treated BC cells. The breast cancer cell lines MCF-7 and MDA-MB-231 were used for analysis of in-vitro functions.

1. Abstract Despite the antibiotic sale prohibition without medical prescription since 2010, excessive and often inappropriate antibiotic prescription and self-medication, are still common practices in Brazil. Indiscriminate antibiotic use is directly involved with the dissemination of resistant bacteria causing serious infections increasingly difficult to treat.

1. Abstract 1.1. Background and Objectives: In the current scenario, there are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on a molecular basis.

1. Abstract 1.1. Background: Cardiac Rehabilitation (CR) is a multidiscipli- nary approach for secondary prevention of coronary heart diseases as well as its comorbid psychological disorders such as depres- sion. Its importance is not well established like other secondary prevention measures although it is one of the most cost-effective methods.