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September 21, 2025


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Pyomyositis; A Rare but Dangerous Adverse Effect of Anabolic Steroids

1. Summary Pyomyositis is an acute bacterial infection of soft tissue and results in intramuscular localized abscess formation. Anabolic steroid injections are frequently used by athletes in recent years despite their well-documented adverse effects. Pyomyositis is one of their infrequently reported side effects.

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Immediate Resolution of Non-Withdrawel Delirium Through Daridorexant: A Report of Two Cases

1. Abstract We report here two cases of older women, 84 and 97 years old, who were admitted to our department for conservative treatment after a fall. Both women developed delirium in the course of the inpatient stay. After administration of 50mg Daridorexant, deliri- um was completely dissolved the next morning. Delirium did not recur even after discontinuation of medication. To the best of our knowledge, this is the first report of the efficacy of Daridorexant in the treatment of delirium. As part of an ongoing study in our department, these observations will be further objectified.

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Infantile Systemic Inflammatory Disease Associated with a De Novo POMP Intragenic Deletion

1. Abstract Proteasome maturation protein (POMP), encoded by POMP, is a protein that functions as a chaperone for proteosome maturation. Pathogenic variants in POMP, are associated with the Proteasome- Associated-Autoinflammatory Syndrome (PRAAS), Keratosis linearis with ichthyosis congenita and sclerosing keratoderma (KLICK) syndrome, POMP-related autoinflammation and immune dysregulation disease (PRAID), and chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE).

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Mathematical Model of Anal Canal for Anal Fistula Surgery

1. Abstract 1.1. Purpose: Surgery is necessary for the treatment of an anal fistula. However, excision of some sphincter muscle would compromise sphincter integrity or function, which is the cause of a reduced success rate in the long term. In order to develop an appropriate surgical plan, a mathematical model that describes the relationship between the internal pressure of the anal canal and the structure of anal sphincters was established in this study.

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Physical Growth of Children in South Korea in the Past Four Decades―Cross-Sectional Vs Longitudinal Data

1. Abstract Children Born in 2001 Grew to 1 Year Old (On Birth-Day) in 2002, 6 Years Old in 2007, —, 19 Years Old in 2020. They Didn’t Grow Instantly To 19 Years Old In 2002. Growth In Stature Is Longitudinal And Not Cross-Sectional In Nature.

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