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1. Abstract The concept about the “therapeutic writing” has its beginning from an autobiographic work, realized in 2003, whose title is Letters to a real interlocutor. My sense.

1. Abstract Bladder cancer is a common malignant disease of the urogenital tract, and over the past few decades, immunotherapy, based on the principle of activating the patient’s immune system to root out malignant cells, has largely changed the treatment of cancer. Anti-PD-1 drugs include monoclonal antibodies against PD-1 and the PD-1 ligand (PD-L1).

1. Abstract Patients with cancer are known to have a poor prognosis when infected with SARS-CoV-2 infection. We aimed in this study to as- sess health outcomes in COVID‑19 patients with different cancers in comparison to non‑cancer COVID‑19 patients from different centers in the United States (US).

1. Summary Breast cancer is a disease in which abnormal breast cells grow out of control and form tumours. If left unchecked, the tumours can spread throughout the body and become fatal.

1. Summary Borderline ovarian tumors (BOT) usually occur in women in reproductive age. In comparison with invasive ovarian cancers, the borderline tumors occur in younger patients, approximately around 50 years of age, but invasive ovarian carcinoma around age 60. Positive prognosis depend on the facts, that in 80% of cases theses tumors are early diagnosed.

1. Abstract Background Fahr’s disease is a progressive neurological degenerative disease characterized by abnormal calcification of basal ganglia. The prevalence of this disease is < 1/1.000.000 people of the general population with those in the age of 40 – 60 being the most prevalent age group.

1. Abstract 1.1. Background: Convalescent plasma (CP) was demonstrated promising benefit for clinical practice involved in efficacy and safety in previous coronavirus pandemics, however, the efficacy of CP from COVID-19 sufferers are still controversial and unascertainable based on current randomized controlled trials (RCTs). The urgent needs for affirmative replies on the efficacy and safety of CP for COVID-19 patients must be developed as soon as possible.

1. Summary Ovarian tumors occur in one third of all women gynecology organs. Out of that borderline ovarian tumors occur in 10 – 15% out of all ovarian tumors. They are tumors with low malignant potential, which are different from benign lesions and malignancies by its’ biological behavior and by histological structure.

1. Abstract Odontogenic Keratocyst (OK) derives from remnants of dental- lamina, aggressive behaviour and recur tendency, mandibular mainly located, ascending angle/branch. Ideal one block surgical resection or physical decompression.

1. Summary This article is going to describe diagnostics and surgical treatment of non-palpable lesions of breast, the statement of limited surgery approach in treatment of breast cancer, mapping of focused lymphatic node in axilla in breast cancer (SBA) and application of new trends of implantation plastic surgery.