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1. Abstract 1.1. Background: Globally, glaucoma is the second leading cause of blindness, next to cataract. As per American academy of ophthalmology study 2014, it was estimated that 76 million people worldwide would suffer from glaucoma by 2020, and it is expected that by 2040 that number will increase to 111.8 million.

1. Abstract 1.1. Background: The hardened red blood cells (RBC)-induced capillary endothelial damage, inflammation, edema, and fibrosis are initiated at birth, and terminate with disseminated tissue hypoxia, acute painful crises, multiorgan failures, and sudden death even at childhood in the sickle cell diseases (SCD).

1. Abstract Sifrim-Hitz-Weiss syndrome [SIHIWES] is a multi-systemic neurodevelopmental disorder caused by heterozygous missense variants in chromodomain helicase DNA-binding protein 4 [CHD4].

1. Abstract 1.1. Background: Majority of Pheochromocytoma (PCC) and paraganglioma (PGL) cases are benign without malignant potential but genetic assessment is recommended for all PCC/PGL patients, because of the associated with ig hereditary germline mutations which play a vital role in pathogenesis of tumorigenesis and metastasis.

1. Summary Carcinoma of pancreas is also called ductal carcinoma, adenocarcinoma, is the most common type of pancreatic cancer, accounting for more than 90 percent of pancreatic cancer diagnoses. This cancer occurs in the lining of the ducts in the pancreas.

1. Abstract The concept about the “therapeutic writing” has its beginning from an autobiographic work, realized in 2003, whose title is Letters to a real interlocutor. My sense.

1. Abstract Bladder cancer is a common malignant disease of the urogenital tract, and over the past few decades, immunotherapy, based on the principle of activating the patient’s immune system to root out malignant cells, has largely changed the treatment of cancer. Anti-PD-1 drugs include monoclonal antibodies against PD-1 and the PD-1 ligand (PD-L1).

1. Abstract The paper examines the results of a psychometrics battery (com- bination of questionnaires) for vocational guidance using a sam- ple of 12531 Greek students with an average age of 15.69 years, SD = 1.19, 52.4% females and 47.6% males who completed the questionnaires between 2015 and 2023.

1. Summary Gallstones are hardened deposits of digestive fluid that can form in your gallbladder. Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder holds a digestive fluid called bile that’s released into your small intestine.

1. Abstract 1.1. Objective: There is a substantial body of literature on fertility outcomes following conventional myomectomy (CM), whereas limited research exists regarding fertility outcomes after Intracapsular Rotary-cut Procedure (IRCP).Our aim was to compare the reproductive outcomes between IRCP and CM.