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1. Abstract 1.1. Background: The hardened red blood cells (RBC)-induced capillary endothelial damage, inflammation, edema, and fibrosis are initiated at birth, and terminate with disseminated tissue hypoxia, acute painful crises, multiorgan failures, and sudden death even at childhood in the sickle cell diseases (SCD).

1. Abstract Increased metabolic disorders are generally linked to the progression of diabetes mellitus (DM). In this study, we looked into the effects of the ethanolic extract of Abrus precatorius (A. precatorius) leaves on liver enzymes and glycaemia in alloxan-induced diabetic male rats.

1. Abstract Sifrim-Hitz-Weiss syndrome [SIHIWES] is a multi-systemic neurodevelopmental disorder caused by heterozygous missense variants in chromodomain helicase DNA-binding protein 4 [CHD4].

1. Abstract 1.1. Background: Majority of Pheochromocytoma (PCC) and paraganglioma (PGL) cases are benign without malignant potential but genetic assessment is recommended for all PCC/PGL patients, because of the associated with ig hereditary germline mutations which play a vital role in pathogenesis of tumorigenesis and metastasis.

1. Summary Carcinoma of pancreas is also called ductal carcinoma, adenocarcinoma, is the most common type of pancreatic cancer, accounting for more than 90 percent of pancreatic cancer diagnoses. This cancer occurs in the lining of the ducts in the pancreas.

I have never associated the term “therapeutic” with the meaning of a resolutory and definitive act for the person, but I have always glimed between it aims the indication of a path to the support and protection of those who live a precarious balance, both in Relation to their physical wellbeing both for their delicate inner condition, for their own self-image.

1. Abstract The concept about the “therapeutic writing” has its beginning from an autobiographic work, realized in 2003, whose title is Letters to a real interlocutor. My sense.

1. Abstract Bladder cancer is a common malignant disease of the urogenital tract, and over the past few decades, immunotherapy, based on the principle of activating the patient’s immune system to root out malignant cells, has largely changed the treatment of cancer. Anti-PD-1 drugs include monoclonal antibodies against PD-1 and the PD-1 ligand (PD-L1).

1. Abstract The paper examines the results of a psychometrics battery (com- bination of questionnaires) for vocational guidance using a sam- ple of 12531 Greek students with an average age of 15.69 years, SD = 1.19, 52.4% females and 47.6% males who completed the questionnaires between 2015 and 2023.

1. Summary Gallstones are hardened deposits of digestive fluid that can form in your gallbladder. Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder holds a digestive fluid called bile that’s released into your small intestine.