February 12, 2024

1. Introduction Diabetes Mellitus (DM) comprises a heterogeneous group of systemic, chronic diseases of unknown cause, with variable degrees of hereditary predisposition and the participation of various environmental factors that affect the intermediate metabolism of carbohydrates, proteins and fats that They are pathophysiologically associated with a deficiency in the quantity, timing of secretion and/or action of insulin [1-10].

1. Case Report Despite recent advances in the treatment of multiple myeloma (MM), the disease remains incurable. Triple class refractory (TCR) patients, defined as refractory to a proteasome inhibitor (PI), immunomodulatory agent (IMiD), and anti-CD38 monoclonal antibody have demonstrated to have especially poor outcomes with a median overall survival of less than 1 year [1-3].