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October 30, 2023

Infantile Systemic Inflammatory Disease Associated with a De Novo POMP Intragenic Deletion

1. Abstract Proteasome maturation protein (POMP), encoded by POMP, is a protein that functions as a chaperone for proteosome maturation. Pathogenic variants in POMP, are associated with the Proteasome- Associated-Autoinflammatory Syndrome (PRAAS), Keratosis linearis with ichthyosis congenita and sclerosing keratoderma (KLICK) syndrome, POMP-related autoinflammation and immune dysregulation disease (PRAID), and chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE).

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Mathematical Model of Anal Canal for Anal Fistula Surgery

1. Abstract 1.1. Purpose: Surgery is necessary for the treatment of an anal fistula. However, excision of some sphincter muscle would compromise sphincter integrity or function, which is the cause of a reduced success rate in the long term. In order to develop an appropriate surgical plan, a mathematical model that describes the relationship between the internal pressure of the anal canal and the structure of anal sphincters was established in this study.

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Physical Growth of Children in South Korea in the Past Four Decades―Cross-Sectional Vs Longitudinal Data

1. Abstract Children Born in 2001 Grew to 1 Year Old (On Birth-Day) in 2002, 6 Years Old in 2007, —, 19 Years Old in 2020. They Didn’t Grow Instantly To 19 Years Old In 2002. Growth In Stature Is Longitudinal And Not Cross-Sectional In Nature.

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