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May 3, 2022

The Role of Mutations on Genes PLAGL1 & ZEP57 in 6q24-Related Transient Neonatal Diabetes Mellitus Syndrome

6q24 Transient Infant Diabetes Syndrome is a type of diabetes that occurs in infants. This form of diabetes is characterized by high blood sugar levels (hyperglycemia) caused by a lack of the hor mone insulin. 6q24 neonatal transient diabetes syndrome is caused by the overactivity (overexpression) of certain genes in an area of the long arm (q) of chromosome 6 called 6q24. Humans inherit two copies of their genes, one from the mother and the other from the father.

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Neuropsychiatric Profiles of Brivaracetam: A Literature Review

Anti-seizure medications (ASMs) can cause cognitive or behav ioral adverse drug reactions, which is a significant consideration when selecting an appropriate ASM. Brivaracetam (BRV) is a newer synaptic vesicle protein 2A ligand, which is expected to have less neuropsychiatric adverse effects due to its mechanism of action. To understand the impact of BRV on cognition and behav ior compared with other ASMs, we conducted literatures searching from PubMed and MEDLINE databases.

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