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June 1, 2020

Nicolau Syndrome Due to Benzathine Penicillin Injection: (A Case Report)

Nicolau Syndrome(NS) is a rare complication of intramuscular injections, which is manifested by pain, edema, and livedoid discoloration of the skin immediately after injection. The pathophysiology of the disease is uncertain, but some studies have suggested, reasons such as embolic vessel occlusion, sympathetic nerve stimulation, inflammation, or mechanical injury. In this paper we report a case of NS following penicillin Injection.

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