Preventive Effect and Safety of Pregabalin for FOLFOX-Related Peripheral Neurotoxicity in Patients with Advanced and Recurrent Colorectal Cancer: The Perpetual Study Estimated by United Sections in Gifu for Colorectal Cancer (Perseus CRC-01 Study)
In patients with colorectal cancer, peripheral nerve symptoms as an adverse effect of oxaliplatin (L-OHP) can result in dose restrictions of L-OHP. Presently, there is no effective cure for the peripheral neuropathy caused by L-OHP. The objective of this study was to investigate the effect of PGN in unresectable and metastatic colorectal cancer patients with peripheral neuropathy.
