https://doi.org/10.47829/ACMCR.2025.141103
Male infertility is a significant factor in approximately 40% of couples experiencing primary or secondary infertility, posing a major biomedical and social challenge.

1. Abstract
It is now known that lifestyle-related diseases are caused by senescence. The International Classification of Diseases, 11th Edition (ICD-11) has coded the item “related to aging,” and aging has come to be considered a disease.

1. Abstract
Lower limb stress fractures (SF) can be challenging for physicians to diagnose due to broad clinical presentation and etiology.

Laparoscopic myomectomy is a minimally invasive option for
managing uterine leiomyomas, favored for its benefits of faster
recovery, less pain, shorter hospital stays, and more favorable cos-
metic appearance of the scar compared to open surgery.

https://doi.org/10.47829/ACMCR.2025.141149

Pineal apoplexy is a condition related to the pineal gland of the brain, characterized by bleeding within this region. The bleeding can be caused by various factors.

This study introduces a novel approach to managing brain haem-
orrhages through the creation of gas-filled nanobubbles that re-
spond to magnetic fields. These magnetic bubbles are designed
to expand and effectively isolate haemorrhages upon activation,
providing surgeons with a ground-breaking tool for controlling
bleeding without the need for manual intervention.

Autism Spectrum Disorder (ASD) is a complex neurodevelopmen-
tal condition characterised by social communication deficits and
repetitive behaviours. Increasingly, research has identified oxida-
tive stress as a critical factor in the pathophysiology of ASD, par-
ticularly its impact on Parvalbumin (PV) interneurons, a class of
GABAergic neurons essential for maintaining the balance between
excitatory and inhibitory signalling in the brain

Glioma stem cells (GSCs) play a pivotal role in tumour heteroge-
neity, resistance to therapy, and recurrence, making them critical
targets in neuro-oncology. Their ability to transition between dif-
ferent states-referred to as plasticity—enables them to evade treat-
ments and contribute to the aggressive nature of gliomas.

Guillain-Barré syndrome (GBS) is a rare disorder that affects the
peripheral nervous system. It typically presents with ascending
limb weakness, areflexia, and, in severe cases, respiratory failure.

Methotrexate (MTX) is a folate inhibitor drug used to treat rheu-
matologic diseases and, at higher doses, as antineoplastic medica-
tion.