1. Case Report
Pembrolizumab is a humanized IgG4 monoclonal antibody targeting the PD-1 receptor, approved for immunotherapy in advanced.

1. Abstract
1.1. Introduction
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract [1]. About 75% of GISTs
harbor activating mutations of KIT and About 10% of GISTs harbor PDGFRA activating mutations [2].

1. Abstract
The purpose of this paper was to describe the clinical application of Natural Psychotherapy (NP) to an 18-year-old Chinese high school student.

1. Abstract
Follicular lymphoma (FL) is the second most frequent non-Hodg kin lymphoma, and until now the best treatment has not been de fined, most studies show an excelent Overal Survival (OS), but relapse is observed at very short time. Thus, actually the goal of most studies is to Increase Progression-free survival (PFS).

1. Abstract
The enzyme Chitotriosidase (Chit) has been used as a marker of macrophage activation, given its high value in plasma of patients with strong phagocytic activity. Intrathecal neuroinflammation has been reported in traumatic brain injury (TBI) and described to persist for days or weeks in humans

https://doi.org/10.47829/ACMCR.2025.141119
Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia in the outpatient setting, predominantly due to parathyroid adenomas.

1. Introduction
Appendiceal mucocele is a very rare entity, which according to the literature is found in only 0.3% of appendectomy specimens. Average age of diagnosis is considered around 50 years,

https://doi.org/10.47829/ACMCR.2025.141123

The anterior teeth play a crucial role in esthetics and function. Patients seeking treatment for compromised upper anterior teeth often present with complex challenges, including attachment loss, bone loss, and gingival recession.

Renal ectopia is a rare condition where a kidney is not in its usual position, often found incidentally. When renal cell carcinoma (RCC) occurs in such kidneys, especially in the sacral area, it poses significant challenges.

https://doi.org/10.47829/ACMCR.2025.141103
Male infertility is a significant factor in approximately 40% of couples experiencing primary or secondary infertility, posing a major biomedical and social challenge.