Whole tumor volume based histogram analysis of ADC for differentitating between WHO grade II and III glioma
The therapeutic approaches and prognosis for gliomas differ con siderably for different tumor grades, it is hence important to accu rately assess glioma grade for treatment planning. In addition to the use of conventional mean value, several studies have reported the use of histogram analysis of ADC in glioma grading [1,2]. How ever only the differentiation between low grade and high grade was concerned, whereas differentiation between grade II and III remains challenging.
Accurate discrimination between high grade gliomas (HGG) and metastatic brain tumor (MET) using noninvasive imaging is essen tial for selecting appropriate surgical and radiotherapy treatments and for determining the treatment response.
The Role of Mutations on Genes PLAGL1 & ZEP57 in 6q24-Related Transient Neonatal Diabetes Mellitus Syndrome
6q24 Transient Infant Diabetes Syndrome is a type of diabetes that occurs in infants. This form of diabetes is characterized by high blood sugar levels (hyperglycemia) caused by a lack of the hor mone insulin. 6q24 neonatal transient diabetes syndrome is caused by the overactivity (overexpression) of certain genes in an area of the long arm (q) of chromosome 6 called 6q24. Humans inherit two copies of their genes, one from the mother and the other from the father.