Issue 8

Neuroendocrine Carcinoma (NEC) of the appendix is extremely rare and its clinical characteristics and treatment strategy have not been well established. Here we present a case of appendiceal NEC with very rapid progression, in which complete remission was achieved by radical surgery followed by systemic chemotherapy.

Chronic obstructive pulmonary disease (COPD) is a major health problem as it causes increasing mortality and morbidity in all countries of the world. Its pathogenetic aspect is characterized by progressive irreversible airflow limitation.

The wave of SARS-CoV-2 is affecting every country in the world in a more or less homogeneous way and one wonders what is the best therapeutic option for the infected patient diagnosed with Glioblastoma Multiforme.

Tumid Lupus Erythematosus (TLE) as a rare variant of Cutaneous Lupus Erythematosus (CLE) is characterized by edematous, urticarial-like annular papules and plaques.

Metastatic lesions of the pancreas are uncommon, accounting for approximately 2% of pancreatic malignancies. The most common primary tumors to give rise to pancreatic metastases are lung cancer, renal cell carcinoma and carcinoma of gastrointestinal origin.