Issue 8

There is evidence that the familial Mediterranean gene (MEFV) M694V mutation plays a role in the susceptibility to Spondyloarthritis (SpA). There is an increased prevalence of SpA among Familial Mediterranean fever (FMF) patients, especially in human leukocyte antigen (HLA)  B27 negative patients carrying the MEFV M694V mutation.

Intestinal cystic pneumatosis is a rare condition characterized by the presence of gaseous cysts in the intestinal wall.

Pontocerebellar Hypoplasia (PCH) refers to a group of rare, progressive, and hereditary neurodegenerative disorders with prenatal onset.

Cutaneous angiosarcoma is a soft tissue sarcoma that presents as a violaceous plaque, resembling a persistent bruise on the head and neck. The hematoma-like lesions are pitfalls that could be the first spy of malignant vascular tumors. The low survival rates of cutaneous angiosarcoma require a recognition as early as possible. We report a case of misdiagnosed cutaneous angiosarcoma of the head, which developed after a car crash and that, was firstly diagnosed as bruise.

Vesicovaginal fistula is a common acquired fistula in obstetrics and gynecology. With the development of obstetric technology, the main cause of vesicovaginal fistula is benign gynecological operation. About 80% of vesicovaginal fistula the caused by abdominal hysterectomy. The treatment of vesicovaginal fistula is surgical repair, which can be done through abdominal (open or minimally invasive) and vaginal. It is usually wait 3-6 months for abdominal or vaginal repair to improve the success rate of surgical repair. Howerer, early repair of vesicovaginal fistula is rare.