Issue 1

53 years old Caucasian male patient with suspected aortic valve stenos is and coexisting left ventricle wall hypertrophy was referred to clinical department of interventional cardiology aiming cardio logical diagnostics and determine further treatment.

1.1. Background: Systemic Sclerosis (SS) is a rare multisystemic disorder with changes in the immune system, vascular and connective tissue. Furthermore, there is an increase in the synthesis and accumulation of collagen and extracellular matrix components in the skin and internal organs, with repercussions on the lungs

A 42 year old woman with three children had a hereditary increased risk for breast cancer. She wanted a prophylactic subcutaneous nipple- sparing mastectomy combined with mastopexi and breast augmentation all in one operation

Cutaneous Leishmaniasis(CL) as an endemic disease is a major health problem in Isfahan, a large province in Iran. To date, pentavalentantimonials are the first line treatment in all types ofleishmaniasis [1]. However, their cost, side effects and the problem with injection route, necessitate furtherstudy.