Volume 15 Archives

Case Report: Pembrolizumab-Induced Epiglottitis in Early Triple Negative Breast Cancer

Leave a Comment / Volume 15 / Ahmed Hadeya, MD

https://doi.org/10.47829/ACMCR.2025.15101 The neoadjuvant use of the immune check point inhibitor (ICI) pembrolizumab has significantly increased the complete pathological response (CPR) rate for early triple negative breast cancer (TNBC). However, pembrolizumab is associated with a variety of immune related adverse events (irAEs).

Case Report: Pembrolizumab-Induced Epiglottitis in Early Triple Negative Breast Cancer Read More »

At-Home, Patient-Applied Collagen–Manuka Honey–Hydroxyapatite Dressing for Post- Mohs Surgical Sites: An Eight-Patient Case Series

Leave a Comment / Volume 15 / Isaac Rodriguez, PhD

1. Abstract Non-melanoma skin cancers commonly affect the lower extremities and scalp, where Mohs micrographic surgery (MMS) often leaves wounds with complex healing challenges due to limited vascularity, thin skin, and patient comorbidities. Secondary.

At-Home, Patient-Applied Collagen–Manuka Honey–Hydroxyapatite Dressing for Post- Mohs Surgical Sites: An Eight-Patient Case Series Read More »

Late-onset Cerebrotendinous Xanthomatosis with Mild Symptoms: A Case Report

Leave a Comment / Volume 15 / Pei Shang, MD

1. Abstract Cerebrotendinous xanthomatosis (CTX) typically presents with infantile diarrhea, juvenile cataracts, and tendon xanthomas. We report a diagnostically challenging case of late-onset CTX in a 48-year-old male presenting with isolated progressive dys arthria as the sole predominant neurological feature. Notably,

Late-onset Cerebrotendinous Xanthomatosis with Mild Symptoms: A Case Report Read More »

Impact of a Glycine and N-Acetyl Cysteine Ethyl Ester Complex on Antioxidant and Inflammation Status and Related Quality of Life Parameters in Healthy Adult

Leave a Comment / Volume 15 / Gerald M. Haase, MD

1. Abstract 1.1. Aim This pilot investigation aimed to assess the impact of a proprietary glycine and N-acetyl cysteine (NAC) ethyl ester complex on quality-of-life (QOL) measures as well as blood levels of antioxidant, inflammatory and toxicant status. Recent evidence.

Impact of a Glycine and N-Acetyl Cysteine Ethyl Ester Complex on Antioxidant and Inflammation Status and Related Quality of Life Parameters in Healthy Adult Read More »

Long-Term Treatment With BRAF/MEK Inhibitors for Pleomorphic Xanthoastro- cytoma Grade 3: A Case Report

Leave a Comment / Volume 15 / Ana Misir Krpan, MD, PhD

1. Abstract 1.1. Background Pleomorphic xanthoastrocytoma grade 3 is rare disease classified as a distinct entity in WHO classification 2016. It is usually refractory to a standard therapy for high grade gliomas and has a dismal prognosis.

Long-Term Treatment With BRAF/MEK Inhibitors for Pleomorphic Xanthoastro- cytoma Grade 3: A Case Report Read More »

Pharmacological Awakening: An indispensable tool for Awake Craniotomy: A Case Report

Leave a Comment / Volume 15 / Kunal Kumar Sharma, MD

1. Abstract Awake craniotomy allows safe and effective resection of brain tumours near eloquent areas. However, achieving timely and reliable intraoperative awakening is crucial, particularly when pre-existing pathologies and sedative agents delay emergence.

Pharmacological Awakening: An indispensable tool for Awake Craniotomy: A Case Report Read More »

Bipolar TURIS Resection of Large Prostates: The Experience of our Team

Leave a Comment / Volume 15 / Georgios Zervopoulos, MD

1. Abstract Bi polar TURIS resection of the prostate is a well-established method, used over the past two decades for the surgical therapy of benign prostate hyperplasia. According to the EAU guidelines it is best to be applied.

Bipolar TURIS Resection of Large Prostates: The Experience of our Team Read More »

Lateral (Counterclockwise) 1440° Testicular Torsion: A Rare Surgical Observation

Leave a Comment / Volume 15 / Ferhat Coban, MD

A 22-year-old male presented with acute right scrotal pain for two hours. Scrotal Doppler ultrasound showed absent intratesticular flow with a “whirlpool” sign. Emergency exploration revealed a markedly edematous and congested testis with a 1440°.

Lateral (Counterclockwise) 1440° Testicular Torsion: A Rare Surgical Observation Read More »

Extrapontine Osmotic Demyelination with Pituitary Necrosis Following Severe Hyponatremia: A Rare Neuroendocrine Intersection

Leave a Comment / Volume 15 / Atul Kapoor, MD

1. Abstract 1.1. Background Osmotic demyelination syndrome (ODS) is a rare but significant complication associated with the rapid correction of hyponatremia. Pituitary necrosis, commonly observed in cases of apoplexy, may manifest in susceptible metabolic conditions but is infrequently documented in association with ODS.

Extrapontine Osmotic Demyelination with Pituitary Necrosis Following Severe Hyponatremia: A Rare Neuroendocrine Intersection Read More »

A Case of Fanconi Syndrome with Multiple Fractures and Height Loss as Main Symptoms Caused by Adefovir Dipivoxil

Leave a Comment / Volume 15 / Yang Fan, MD

1. Abstract We present a case of a 57-year-old male who experienced ex- tensive bone pain, difficulty in getting up, weakness in walking, and height loss. He had been taking adefovir dipivoxil tablets for the treatment of hepatitis B.

A Case of Fanconi Syndrome with Multiple Fractures and Height Loss as Main Symptoms Caused by Adefovir Dipivoxil Read More »

Annals of Clinical and Medical Case Reports®

Volume 15