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February 22, 2025


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Volume 14

Successful Desensitization to Pembrolizumab in Patients with Severe Hypersensitivity Reactions, one of Them with Mastocytosis: Report of Three Cases and Review of The Literature

1. Case Report Pembrolizumab is a humanized IgG4 monoclonal antibody targeting the PD-1 receptor, approved for immunotherapy in advanced cancers (melanoma, non-small cell cancer, Hodgkin lymphoma, bladder cancer, etc.) [1].

Successful Desensitization to Pembrolizumab in Patients with Severe Hypersensitivity Reactions, one of Them with Mastocytosis: Report of Three Cases and Review of The Literature Read More »

Physiological And Behavioral Changes of a Black Faced Baboon at Around Critical Wound Surgery

1. Abstract on Physiological and Behavioral Changes of a Black Faced Baboon at Around Critical Wound Surgery This study investigates the physiological and behavioral changes in a critically wounded black-faced baboon (weighing 36 kg) that underwent surgery for perforated injuries to the umbilicus, lips, and buttocks.

Physiological And Behavioral Changes of a Black Faced Baboon at Around Critical Wound Surgery Read More »

Characteristics of Bronchiectasis Patients at Nguyen Tri Phuong Hospital Ho Chi Minh City, Vietnam

1. Abstract 1.1. Introduction Bronchiectasis, significant in morbidity and mortality, varies globally in demographics, microbiology, and causes. This study at Nguyen tri Phuong Hospital assessed clinical aspects and etiologies of bronchiectasis in adults.

Characteristics of Bronchiectasis Patients at Nguyen Tri Phuong Hospital Ho Chi Minh City, Vietnam Read More »

Natural Psychotherapy, A Novel Psychotherapy with Eastern Cultural Characteristics, for A Complex Case of Obsessive – Compulsive Disorder: A Case Report

1. Abstract The purpose of this paper was to describe the clinical application of Natural Psychotherapy (NP) to an 18-year-old Chinese high school student with refractory obsessive-compulsive disorder (OCD) associated with cell phone addiction, depersonalization disorder, and transvestism.

Natural Psychotherapy, A Novel Psychotherapy with Eastern Cultural Characteristics, for A Complex Case of Obsessive – Compulsive Disorder: A Case Report Read More »

Pleomorphic Hyalinizing AngiectaticTumor: A Case Report and Literature Review

1. Abstract Pleomorphic hyalinizing angiectatictumor (PHAT), a rare low-grade non-metastasizing tumor, was first reported in 1996[1]. It affects patients with a mean age of 54.5 years and no predilection for gender[2], and has a preference for the subcutaneous soft tissue in the lower extremity.

Pleomorphic Hyalinizing AngiectaticTumor: A Case Report and Literature Review Read More »

A 57-Year-Old Man with Mycobacterium Mageritense and Pneumocystis Jirovecii Coinfection after Loss to Follow-Up for 9 Years

1. Abstract Future randomized controlled trials are required to develop better treatment strategies. Herein, we present a case of pneumonia caused by M. mageritense. A 57-year-old man with a history of being a human immunodeficiency virus (HIV) carrier and who had been irregularly followed up in outpatient clinics for approximately 9 years was previously treated with Kaletra and Kivexa.

A 57-Year-Old Man with Mycobacterium Mageritense and Pneumocystis Jirovecii Coinfection after Loss to Follow-Up for 9 Years Read More »

An Unusual PDGFRA Mutation in Gastrointestinal Stromal Tumor and Its NGS Data Analysis

1. Abstract 1.1. Introduction Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract [1]. About 75% of GISTs harbor activating mutations of KIT and About 10% of GISTs harbor PDGFRA activating mutations [2]. PDGFRA is the second most mutated oncogene in GIST and are particularly associated with gastric tumors [3,4].

An Unusual PDGFRA Mutation in Gastrointestinal Stromal Tumor and Its NGS Data Analysis Read More »

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