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February 22, 2025


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Meta-analysis of first-line Antiretroviral Treatment Failure in Adult HIV Patients in Ethiopia following Implementation of the ‘Universal Test and Treat Strategy

1. Abstract 1.1. Background: With ART programs expanding significantly under test-and-treat strategies, treatment failure is on the rise. In Ethiopia, studies assessing first-line ART failure and associated factors show varying findings, leading to inconsistencies in reported magnitudes.

Meta-analysis of first-line Antiretroviral Treatment Failure in Adult HIV Patients in Ethiopia following Implementation of the ‘Universal Test and Treat Strategy Read More »

Case Report: Chemotherapy and PD-1 Inhibitor-Induced Tumor Lysis Syndrome in Primary Hepatic Sarcomatoid Carcinoma

1. Abstract Primary Hepatic Sarcomatoid Carcinoma is a rare and highly aggressive tumor with a poor prognosis, primarily diagnosed through meticulous histopathological examination and extensive immunohistochemical analysis.

Case Report: Chemotherapy and PD-1 Inhibitor-Induced Tumor Lysis Syndrome in Primary Hepatic Sarcomatoid Carcinoma Read More »

Physiological And Behavioral Changes of a Black Faced Baboon at Around Critical Wound Surgery

1. Abstract on Physiological and Behavioral Changes of a Black Faced Baboon at Around Critical Wound Surgery This study investigates the physiological and behavioral changes in a critically wounded black-faced baboon (weighing 36 kg) that underwent surgery for perforated injuries to the umbilicus, lips, and buttocks.

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Successful Desensitization to Pembrolizumab in Patients with Severe Hypersensitivity Reactions, one of Them with Mastocytosis: Report of Three Cases and Review of The Literature

1. Case Report Pembrolizumab is a humanized IgG4 monoclonal antibody targeting the PD-1 receptor, approved for immunotherapy in advanced cancers (melanoma, non-small cell cancer, Hodgkin lymphoma, bladder cancer, etc.) [1].

Successful Desensitization to Pembrolizumab in Patients with Severe Hypersensitivity Reactions, one of Them with Mastocytosis: Report of Three Cases and Review of The Literature Read More »

LHX4 Mutation: New Perspective

1. Abstract Some transcription factors orchestrate the ontogeny of the pituitary gland, maintain the differentiated state and mediate the coordinated expression of specific cell type and their alteration can be involved in isolated and combined deficits. Among them, LHX4 gene mutations can manifest as a combined pituitary hormone deficiency and are associated with an ectopic posterior pituitary and/or a sella turcica defect.

LHX4 Mutation: New Perspective Read More »

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