Integration of AI-Driven ǪSAR Modelling and Organ-on-Chip Technology in Ophthalmic Medicine

1. Abstract AI-driven pharmacology in ophthalmology addresses critical challenges in drug discovery for ocular diseases like age-related macular degeneration (AMD) and diabetic retinopathy, where physiological barriers and complex biomarkers hinder tradition- al methods. This review outlines AI’s role in accelerating tar- get identification, lead optimization, and clinical translation to enhance precision medicine and reduce development timelines.

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