October 3, 2021

COVID-19 can cause different clinical manifestation by affecting different organs in the body. Involvement of thyroid gland is very rare in COVID-19 infection than any other systems of the body. We described a 41-year-old female with subclinical thyroiditis most likely related to corona virus infection and reviewed literatures regarding cases of thyroiditis due to COVID-19 have been reported. The objective of this article is to create awareness regarding this novel entity and the association with thyroid dysfunction.

Mandibulofacial dysostosis with microcephaly, Guion-Almeida type (MFDGA) is a rare multiple congenital anomalies syndrome characterized by malar and mandibular hypoplasia, microcephaly, ear malformations with associated conductive hearing loss, esophageal atresia, cleft palate and distinctive facial dysmorphism. Almost all affected individuals have developmental delay and intellectual disability.

Patients with disease progression on first-generation tyrosine kinase inhibitors (TKIs) usually have a poor prognosis. The mechanisms of acquired resistance to epidermal growth factor receptor (EGFR)-TKIs have been widely reported; however, reports of acquired