Drug Resistance, An Enemy of Targeted Cancer Therapies
The success of targeted cancer therapies will depend on the uniformity of the target cells. Cancer cells mutate and potentially can alter that target, defeating that therapy. A means of computing the number of altered targets and what may be necessary to improve the probability of successful treatment is presented. This analysis indicates that single drug, targeted therapy will not be successful unless the cancer can be treated in very early stages with low cancer cell counts.
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