Cytokine storm syndrome in COVID-19 patients: Characteristics and Diagnosis
Cytokine storm syndrome (CSS) is a critical condition induced by a cascade of cytokine activation, characterized by overwhelming systemic inflammation, hyperferritinaemia, haemodynamic instability and multiple organ failure. At the end of 2019, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, and rapidly developed into a global pandemic. There is a dramatic increase of inflammatory cytokines in patients with COVID-19, suggesting the existence of cytokine storm in some critical illness patients. Here, we summarize the pathogenesis, clinical manifestation of CSS, and highlight the current understanding about the recognition and diagnosis of CSS in COVID-19.
Cancer cells – their origin
The formation of cells in the body, like their mutation, is a process associated with a violation of the composition and structure of a substance (cells) formed under the influence of an external field surrounding it
Plea for an Air-Microbubbles and Air-Blood Interface Free Hemodialysis
Air microbubbles are common in the haemodialysis venous return line, especially in the very first minutes of HD session and with high blood flows. They might be damaging for the lungs microcirculation and stimulate the inflammation system
The Effect Of Working From Home As A Result Of Covid-19
The coronavirus pandemic hit the world unexpectedly, and to respond swiftly to it, lockdown and social distancing measures had to be implemented to combat its spread
Complement enhances the pathogenesis in autoinflammation via induction of a pro-inflammatory microenvironment
The complement system is a complex part of the innate immune system and consists of more than thirty different proteins present in the plasma and on cell membranes. Complement can be activated via three different pathways and may play a role in triggering the NLRP3 inflammasome [1]. Inflammasomes are essential components in innate immunity.
Rural Healthcare in Light of a Multinational Pandemic: A Global Perspective
Rural healthcare recently came into international spotlight, with recent reported influx of the COVID-19 into rural regions. This article focuses on susceptibilities of the rural population to pandemics and mitigating measures to prevent formation of disease epicentre. Rural Healthcare is by far one of the most neglected areas of medicine
The nature of Primary Care
It’s important to define what Primary Care is and the priorities and context in which Primary Care works. After few but important and cornerstone words on Primary Care as in Alma Ata Declaration, we needed a Document defining what General Practice is and its competencies, a really authoritative view on what family doctors in Europe should be providing in the way of services and health to patients, at the highest quality and cost effective.
The Assessment of the Whole-Body Vibration on Health Effects in Automobile Assembly Line Worker in South Korea
1.1. Background: In general, whole-body vibration is one of the potential contributors to the development of back disorders of workers. In particular, it is thought that workers at the automobile assembly line are exposed to mechanically induced vibrations, either Whole-body Vibration (WBV) or Hand-arm Vibration (HAV). However, we can not assess the WBV on health effects in automobile assembly line workers.
Cognitive consequences after traumatic brain injury (TBI)
A traumatic brain injury (TBI) can cause temporary dysfunction of brain cells. More severe craniocerebral injuries can lead to bruising, perforation and tissue rupture, bleeding, and other physical damage to the brain that can lead to long-term complications or death (Bigler, 2016). Consequences of TBI can include physical, sensory, behavioral, and communication disorders, as well as disturbances in cognitive functioning.
Patients with Multiple Sclerosis and short-term memory difficulties
Μemory by itself as a function, loses its capabilities with a normal deterioration. However, there are acquired conditions that negatively affect the functions of memory, resulting in dysfunction of its stages.