Multicentric and Prospective Trial of Vulvovaginitis Treatment Comparing Propionibacterium Extract [Immunovag®] With Metronidazole Plus Clotrimazole [Meclon®]
Vulvo-Vaginal Infections [VVI] strongly interferes with the wom an’s quality of life. Antibiotic treatments, alone or combined with an antifungal compound, are commonly and successfully used. Nevertheless, they can impair genital microbiota, with long-term disorders, such as a flare-up of genital disturbances due to chang es of endogenous lactobacilli. Alternatively, probiotics have been proposed. This prospective multicenter double-arm study, per formed in 72 premenopausal women diagnosed with VVI, whose etiology was Gardnerella Vaginalis (n=9), Candida Albicans (n=21), or Bacterial Vaginosis (n=42), was performed to com pare the clinical efficacy of a short-term treatment with a vaginal gel containing the bacteria lysate obtained by Propionibacterium acnes [Immunovag®, Depofarma, Mogliano Veneto, Italy] given for 5 days (n=40) with that of vaginal suppositories containing metronidazole and clotrimazole [Meclon®, Alfasigma SPA, Bo logna, Italy] given for 6 days (n=32). The study was conducted at the gynecological Departments of the University-Hospitals of Cagliari, Catania, Catanzaro, Genova and Modena – Reggio Emilia [Italy]. At post-treatment evaluation (10 days from the screening and randomization), regardless of VVI etiology and type of treat ment, a significant decrease (p
Shoulder Injury Related to Vaccine Administration After Covid-19 Vaccination: A One-Year Observational Single-Center Study
Due to widespread vaccination caused by the global COVID-19 pandemic, a large proportion of the population has experienced shoulder pain after vaccination. Shoulder injury related to vaccine administration (SIRVA) may occur when the vaccine is not ad ministered properly. The electronic medical data of patients with shoulder pain who visited the pain Department of the First Affiliat ed Hospital of Soochow University from April 1, 2021 to April 1, 2022 were queried. Vaccination details, Numerical Scoring Scale (NRS), and Constant-Murley score were collected at baseline and at 1, 3, and 6 months’ post-treatment follow-up.
The prevalence of chronic kidney disease (CKD) has steadily in creased and diabetes is now considered the leading cause of end stage kidney disease (ESRD). Glycemic control in chronic renal patients on dialysis presents additional difficulties because both uremia and dialysis can affect insulin secretion and tissue insulin sensitivity. In dialysis patients, blood glucose measurement may be affected as hemodialysis causes rapid and marked changes in body fluid volume, including subcutaneous and interstitial tissue.
Aim: This study compared the characteristics of older and younger patients with sepsis and analyzed the risk factors associated with 28-day and 90-day mortality in critically ill patients.
1.1. Aims: The aim of this study was to analyze the association between mental health and dental caries in graduate students in China. 1.2. Methods: Three structured psychological scales, includ ing the Symptom Checklist 90, Perceived Social Support Scale, and General Well-Being Schedule were administered to evaluate mental health. Dental caries consists of three parts, oral question naires, caries susceptibility tests and caries examinations. Oral questionnaires assessing oral health, oral hygiene, and oral habits were regarded as potential confounding factors. Cariostat caries susceptibility test was used to evaluate caries susceptibility.
Starting with December 2019 the medical world has faced a new challenge as a consequence of a new type of coronavi rus-2019-nCoV, similar to several familiar strains that determine a comparable symptomatology (SARS- severe acute respirato ry syndrome, MERS- Middle East severe acute respiratory syn drome), subsequently named SARS CoV-2, while the disease it causes- COVID-19. The virus is of animal origin and through an intermediate host (probably also a mammal) it suffered genetic changes thus acquiring human cells receptors.
This study investigates the prevalence of psychological comorbid ity in patients with moderate to severe psoriasis vulgaris. Further more, the relation between the type of disorder and the degree of psoriasis severity has been analysed. In 10 German study sites 137 female (61 = 44.5%) and male (76=55.5%) patients that had been diagnosed with moderate or severe psoriasis by a qualified derma tologist were surveyed. The most frequent observed comorbidities were moderate to severe depressive syndromes (23.4%), followed by alcohol syndromes (5.8%) and panic disorders (4.6%). Analysis of relations between the type and severity of disorder and the de gree of psoriasis severity showed no significant correlations. The present data confirm the psychosocial stress of patient with psori asis regardless of the degree of severity.