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Pharmacokinetics of Methotrexate during Chemotherapy Administration in a Patient with Acute Lymphoblastic Leukemia

1. Case Series A 36-year-old male with a past medical history of Acute Lymphoblastic Leukemia and type 2 diabetes was transferred to the Upstate Medical University Hospital for continuation of chemotherapy. The patient initially presented to a local hospital with epistaxis and was originally treated for immune thrombocytopenic purpura with intravenous immunoglobulins and steroids. DOI: […]

Bacteremia due to Serratia Rubidaea in ICU: Case series

Bacteremia due to S.Rubidaea is rarely described comparing with other species of Enterobacteriacae. It interests immunocompro mised patients undergoing invasive procedures. Herein, we report four cases of bacteraemia due to this pathogen in patients admitted in ICU for ketoacidosis with history of diabetes mellitus.Common ly, a catheter-related infection complicated with deep vein throm bosis was present. Catheter site was femoral in all four cases. All patients were female. Commonly, a poorly-tolerated fever was the main clinical manifestation. The pathogen was isolated in several peripheral blood cultures (>4) for the same patient with the same profile in all four cases.

Modified Elmslie-Trillat Technique for Knee Cap Dislocation: A Retrospective Study with 5 Patients and 1 Year Follow-Up

Knee cap dislocation is a common orthopedic injury that can lead to significant pain, instability and knee dysfunction. Surgical man agement of knee cap dislocation involves various techniques in cluding anteromedialisation and arthroscopic lateral release. The modified Elmslie-Trillat technique combines these two procedures for a more comprehensive and effective treatment. The aim of this retrospective study was to evaluate the clinical outcomes of the modified Elmslie-Trillat technique for knee cap dislocation in a series of 5 patients.

The Superiority of Amniotic Membrane in the Treatment of Aplasia Cutis Congenita

1.1. Introduction: Aplasia cutis congenital (ACC) is a heteroge neous group of disorders that share a common feature of focal skin loss. In most cases, this is limited to the scalp, also involve other parts of the body. (ACC) is a heterogeneous group of disorders whose common characteristic is focal absence of skin. In the ma jority of instances this is limited to the scalp, although other areas of the body may also be involved. It is characterized by a lack of skin and adjacent tissues, and it can extend into underlying tis sues, such as muscle tissue and bone, that can be underdeveloped or even absent. ACC can be life-threatening in severe cases. Both conservative and surgical approaches carry risks, and the timing of surgery remains controversial.

Cardiac Myxoma: A Rare Case Series of 4 Patients and a Literature Review

Cardiac myxomas are the most common primary cardiac tumor. Clinical findings are numerous and range from general manifesta tions to symptoms related to intra-cardiac obstruction or systemic embolization. Echocardiography is the key exam for the diagnosis and surgery allows tumor resection and the prevention of compli cations.

Cyclosporine Attenuates Covid-19: Ensnare or Victory

Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS). I

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