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Neoadjuvant therapy for HER-2 positive acantholytic squamous cell carcinoma of the breast: a case report

HER2-positive breast ASCC is exceptionally rare, its clinico pathological characteristics are insufficiently studied, and the im plications of neoadjuvant therapy, comprising targeted treatment against HER2. Here we reported that a 58-year-old woman with a histopathological diagnosis of HER2-positive ASCC gave a neo adjuvant therapy of albumin-paclitaxel, carboplatin in conjunction with trastuzumab every 3 weeks.

McKittrick-Wheelock Syndrome:A rare occasion in a young patient

Mckittrick-Wheelock syndrome is a fatal and life threatening diag nosis if no interventions taken on time. It is due to a large distal co lon polyp that secretes body salts including sodium and pottasium and thus, causing severe diarrhea and dehydration to the patient.

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