Issue 4

1.1. Objective: Some studies reported GTP2 gene missense mu tations are associated with neurodevelopmental delay with spastic paraplegia and microcephaly. Here, we report a new frameshift mutation of this gene with new clinical presentations in an Iranian family

Epithelioid Angiosarcoma (EA) is a special subtype of angiosar coma, which is common in skin and connective tissue, and its in cidence reaches the peak in men aging over 60 years old. EA oc curring in masticator space was very rarely reported. We reported EA in a young woman with a lesion located in the right masticator space. Plain Computed Tomography (CT) scan showed irregular blocky soft tissue density shadow with unclear boundary. After enhancement, the lesions showed obviously uneven enhancement in the arterial phase, while the lesions showed uneven decreased enhancement in the venous phase, and there was necrotic tissue with no enhancement.

1.1. Background: Spinocerebellar ataxia type 5 (SCA5), domi nant spinocerebellar ataxia caused by mutations in the SPTBN2 gene, SCA5 is clinically described as a slowly progressive cere bellar ataxia with little involvement of the brainstem or spinocere bellar tract or brain, occurring mainly in adulthood.

This research is written by a person with Type 1 Diabetes diag nosed 44 years ago, treated with insulin 43 years, and with a 50- year career in healthcare.

Aim: This study compared the characteristics of older and younger patients with sepsis and analyzed the risk factors associated with 28-day and 90-day mortality in critically ill patients.

In ten years after the end of WWII, Japan’s economy recovered to the prewar level and achieved fast and steady progress toward the 1990s. People, the young in particular learned to eat animal prod ucts and the teens grew in height nearly 10 cm by the early-1990s and plateaued in stature after that. South Korea was two decades behind Japan in economic development due to the Korean War (1950-53) and then has achieved uninterrupted progress to parallel with Japan in respect of living standard by the turn of the century.